Ligand-free CuO nanospindle catalyzed arylation of heterocycle C-H bonds.
Ligand-free CuO nanospindle catalyzed arylation of heterocycle C-H bonds.
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DOI：
10.1021/jo200452x
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发表时间：
2011-05
期刊：
影响因子：
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通讯作者：
Wu Zhang;Q. Zeng;Xinming Zhang;Yujie Tian;Y. Yue;Yujun Guo;Zhenghua Wang
中科院分区：
文献类型：
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作者：
Wu Zhang;Q. Zeng;Xinming Zhang;Yujie Tian;Y. Yue;Yujun Guo;Zhenghua Wang
制备了氧化铜纳米纺锤体，用于催化杂环碳氢键的直接芳基化，收率中等至优异。在无配体的催化条件下，该反应可以在更环保的无机碱(如K（2)CO(3)）存在的情况下应用于杂环化合物，如苯并恶唑、苯并噻唑和1-甲基苯并咪唑。此外，该催化剂可以回收再利用，而催化活性没有明显下降。
CuO nanospindles have been developed to efficiently catalyze the direct arylation of heterocycle C-H bonds with moderate to excellent yields. This reaction can be applied to heterocycles such as benzoxazole, benzothiazole, and 1-methylbenzimidazole in the presence of a more environmentally friendly inorganic base like K(2)CO(3) under ligand-free catalytic conditions. In addition, the catalyst can be recycled and reused without any significant decrease in catalytic activity.