20-Hz Flicker Stimulus Can Isolate the Cone Function in Rat Retina
20-Hz Flicker Stimulus Can Isolate the Cone Function in Rat Retina
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20 Hz 闪烁刺激可分离大鼠视网膜中的视锥细胞功能
DOI：
10.1159/000055497
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发表时间：
1998
影响因子：
2.1
通讯作者：
Motohiro Kato
中科院分区：
文献类型：
--
作者：
Y. Goto;T. Yasuda;S. Tobimatsu;Motohiro Kato
视锥视网膜电信号(ERG)在人类中通常是通过针对视杆脱敏适应野的闪烁刺激而分离出来的。为了研究适应野亮度对视锥ERG的影响方式，我们记录了正常白化SD大鼠的ERG，在适应野的亮度范围从-∞到1.75logCd/m2的闪光刺激下。在所有适应条件下，使用20赫兹的闪烁频率来分离视锥ERG。我们发现，视锥ERG的幅度随着适配场亮度的增加而增加。这些反应特征类似于使用30赫兹闪烁刺激的人类ERG，这表明闪烁刺激是分离大鼠视锥功能的一种有用的技术。
Cone electroretinograms (ERGs) are typically isolated in humans by flicker stimuli against rod-desensitizing adapting fields. To investigate the manner in which adapting-field luminance affects the cone ERGs, we recorded ERGs in normal albino Sprague-Dawley rats with flicker stimuli presented against adapting fields that ranged in luminance from –∞ to 1.75 log cd/m2. A flicker rate of 20 Hz was used to isolate the cone ERGs under all adaptation conditions. We found the amplitudes of cone ERGs to increase with increasing adapting-field luminance. These response characteristics are similar to human ERGs using 30-Hz flicker stimuli, which suggests that flicker stimuli are a useful technique to isolate the cone function in rats.
表达突变视紫红质基因的转基因小鼠的功能异常。
影响因子：
4.4
作者：
Goto,Y;Peachey,NS;Ripps,H;Naash,MI
通讯作者：
Naash,MI