Childhood abuse and early menarche: findings from the black women's health study.

Childhood abuse and early menarche: findings from the black women's health study.
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DOI:
10.2105/ajph.2008.149005
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发表时间:
2009-10
影响因子:
12.7
通讯作者:
Rosenberg L
Rosenberg L
中科院分区:
医学2区
文献类型:
--
作者:
Wise LA;Palmer JR;Rothman EF;Rosenberg L

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我们以美国黑人女性为样本,研究了童年虐待和月经初潮之间的关系。我们对黑人妇女健康研究中35330名参与者的数据进行了多变量对数二项回归,以估计儿童身体虐待和性虐待与初潮年龄(即<12岁)之间关系的风险比和95%置信区间。在调整分析中,性虐待与月经初潮早期呈正相关,并且随着性虐待事件频率的增加,月经初潮早期的风险增加。我们观察到身体虐待和月经初潮之间存在微弱但有统计学意义的关联。当我们使用更严格的月经初潮的临界值(即<11岁)时,性虐待与早期月经初潮之间的关联更强。我们的数据表明,经历过儿童期性虐待的黑人妇女月经初潮的风险增加。儿童时期的身体虐待和月经初潮早期之间的联系的证据是模棱两可的。
We examined the association between childhood abuse and early menarche in a sample of US Black women. We conducted multivariable log-binomial regression on data from 35330 participants in the Black Women’s Health Study to estimate risk ratios and 95% confidence intervals for the relation of childhood physical and sexual abuse with early age at menarche (i.e., <12 years). In adjusted analyses, sexual abuse was positively associated with early menarche, and the risk of early menarche increased with increasing frequency of sexual abuse incidents. We observed a weak but statistically significant association between physical abuse and early menarche. Associations between sexual abuse and early menarche were stronger when we used a more stringent cutpoint for early menarche (i.e., <11 years). Our data suggest an increased risk of early menarche among Black women who experienced childhood sexual abuse. Evidence for an association between childhood physical abuse and early menarche was equivocal.