One-pot Suzuki coupling of aromatic amines via visible light photocatalyzed metal free borylation using t-BuONO at room temperature
One-pot Suzuki coupling of aromatic amines via visible light photocatalyzed metal free borylation using t-BuONO at room temperature
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DOI：
10.1016/j.tetlet.2016.02.097
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发表时间：
2016-04-06
影响因子：
1.8
通讯作者：
Ranu, Brindaban C.
中科院分区：
文献类型：
--
作者：
Ahammed, Sabir;Nandi, Shiny;Ranu, Brindaban C.
在室温下，以亚硝酸叔丁酯和B（2）Pin（2）（双（频哪醇合）乙硼烷）为催化剂，在蓝光照射下，实现了芳香胺的方便、高效的无金属硼化反应.该方案已成功地扩展到随后的Suzuki偶联在同一锅。因此，在较短的反应时间内以高产率从相对便宜的芳基胺开始在一锅中获得一系列官能化的芳基硼酸酯和联芳基化合物，避免了分离潜在不稳定和危险的中间体。(C)2016爱思唯尔有限公司版权所有
A convenient and efficient metal free borylation of aromatic amines has been achieved using tertiary butyl nitrite and B(2)Pin(2) (bis(pinacolato)diborane) under irradiation with blue LED light at room temperature. This protocol has been successfully extended to subsequent Suzuki coupling in the same pot. Thus a series of functionalized aryl boronates and biaryls are obtained in high yields in a shorter reaction period starting from relatively cheap aryl amines in one-pot avoiding isolation of potentially unstable and hazardous intermediates. (C) 2016 Elsevier Ltd. All rights reserved.