Gelsemium elegans Poisoning: A Case with 8 Months of Follow-up and Review of the Literature.

Gelsemium elegans Poisoning: A Case with 8 Months of Follow-up and Review of the Literature.
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钩吻中毒:8个月随访及文献复习一例

DOI:
10.3389/fneur.2017.00204
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发表时间:
2017
影响因子:
3.4
通讯作者:
Zhang W
Zhang W
中科院分区:
医学3区
文献类型:
--
作者:
Zhou Z;Wu L;Zhong Y;Fang X;Liu Y;Chen H;Zhang W

文献摘要

被引文献

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Background Gelsemium elegans (G. elegans) is a toxic plant indigenous to Southeast Asia. It is highly poisonous due to its strong respiratory depressive effect. However, G. elegans poisoning cases have not been summarized comprehensively and are rarely reported in English journals. Furthermore, none of the present reports present prognosis in detail. Case presentation A 26-year-old female was found comatose at home and brought to the hospital with deep coma, hypoxia, and acidosis. After mechanical ventilation for hours, the patient recovered from coma with sequelae of impaired short-term memory, disorientation, and childish behaviors. Brain magnetic resonance imaging (MRI) showed bilateral hippocampus and basal ganglia damage due to hypoxia. During 8 months of follow-up, both her symptoms and brain MRI scan improved significantly. Conclusion G. elegans is highly toxic. Although patients may die within 30 min due to its strong respiratory depressive effect, they can survive with timely respiratory support and enjoy gradual improvement without delayed postanoxic encephalopathy.