Increased energy/activity, not mood changes, is the core feature of mania
Increased energy/activity, not mood changes, is the core feature of mania
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DOI：
10.1016/j.jad.2013.09.021
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发表时间：
2014-01-01
影响因子：
6.6
通讯作者：
Landeira-Fernandez, J.
中科院分区：
文献类型：
--
作者：
Cheniaux, Elie;Filgueiras, Alberto;Landeira-Fernandez, J.
背景资料：在《精神疾病诊断与统计手册》（第5版）中，能量/活动增加和情绪波动或易激惹的出现成为诊断躁狂或轻躁狂发作的必要症状。目的：评价能量/活动增加或情绪变化是否代表躁狂综合征的核心特征。采用改良版情感障碍和精神分裂症量表（SADS-C）对117例双相躁狂住院患者进行精神病学评价。根据SADS-S中与躁狂症相关的6个条目，进行验证性因素分析（CFA）。项目反应理论（IRT）分析被用来确定有多少每个症状通知不同级别的严重程度syndrome.Results：根据CFA，项目“增加能源”是最高的因子负荷的症状，这是证实了IRT分析。因此，能量增加是与躁狂症状总的严重程度最相关的改变。此外，项目信息功能的分析显示，增加能量与更大幅度的严重程度水平相比，其他症状mania.Limitations：只有6躁狂症状被认为是。样本可能不具有代表性，因为患者进行了评估，同时提出高峰期症状severity.Conclusions：增加能量/活动是一个更重要的症状诊断躁狂症比情绪变化，并代表这种综合征的核心特征。(C)2013爱思唯尔有限公司版权所有。
Background: In the Diagnostic and Statistical Manual of Mental Disorders, 5th edition, the occurrence of increased energy/activity and elation of mood or irritability became necessary symptoms for the diagnosis of an episode of mania or hypomania.Objective: To evaluate whether increases in energy/activity or mood changes represent the core feature of the manic syndrome.Methods: The symptomatology of 117 hospitalized patients with bipolar mania was evaluated using the Schedule for Affective Disorders and Schizophrenia Changed version (SADS-C). Based on six items of the SADS-S related to mania, a Confirmatory Factor Analysis (CFA) was performed. An Item Response Theory (IRT) analysis was used to identify how much each symptom informs about the different levels of severity of the syndrome.Results: According to the CFA, the item "increased energy" was the symptom with the highest factorial loadings, which was confirmed by the IRT analysis. Thus, increased energy was the alteration most correlated with the total severity of manic symptoms. Additionally, the analysis of the Item Information Function revealed that increased energy was correlated with the larger amplitude of severity levels compared with the other symptoms of mania.Limitations: Only six manic symptoms were considered. The sample might not be representative because the patients were evaluated while presenting peak symptom severity.Conclusions: Increased energy/activity is a more important symptom for a diagnosis of mania than mood changes and represents the core feature of this syndrome. (C) 2013 Elsevier B.V. All rights reserved.