MEASUREMENT AND USE OF ACOUSTIC NONLINEARITY AND SOUND SPEED TO ESTIMATE COMPOSITION OF EXCISED LIVERS
MEASUREMENT AND USE OF ACOUSTIC NONLINEARITY AND SOUND SPEED TO ESTIMATE COMPOSITION OF EXCISED LIVERS
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DOI：
10.1016/0301-5629(86)90004-9
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发表时间：
1986-11-01
影响因子：
2.9
通讯作者：
GREENLEAF, JF
中科院分区：
文献类型：
--
作者：
SEHGAL, CM;BROWN, GM;GREENLEAF, JF
在20 - 37 ° C下测定了切除的正常和异常人肝的声学非线性参数B/A和声速c。C.将这些值与组织的脂肪和水含量的分析测量值进行比较。结果表明，含有71.0%重量的水和2.9%重量的脂肪的正常肝脏具有6.75的B/A值和在37 °的1592 m/s的声速。C.这两个参数以0.026 °的平均速率增加。1.5 m/s/℃。当温度从20 ℃升高到37 ℃时，C.脂肪肝（24%脂肪重量）表现出最高的B/A（9.12）和最低的c（1522 m/s）的所有研究的肝脏。与正常肝脏相反，发现在这样的肝脏中声速随温度降低。基于声学和成分测量，已经开发了B/A和c与脂肪-水组成的定量关联。这些关系的反演提供了从B/A和c测量确定组织样品的组成的简单方法。
The acoustic nonlinearity parameter B/A and sound speed c have been determined for excised normal and abnormal human livers at 20-37.degree. C. These values are compared with analytic measurements of fat and water content of tissues. The results show that normal liver containing 71.0% water and 2.9% fat by weight has a B/A value of 6.75 and sound speed of 1592 m/s at 37.degree. C. Both these parameters increase at an average rate of 0.026.degree. C and 1.5 m/s/.degree. C, respectively, as the temperature is raised from 20 to 37.degree. C. Fatty liver (24% fat by weight) exhibits highest B/A (9.12) and lowest c (1522 m/s) of all the livers studied. In contrast to normal livers sound speed in such a liver was found to decrease with temperature. Based on the acoustic and composition measurements, quantitative correlations of B/A and c with fat-water composition have been developed. Inversion of these relationships provide a simple method to determine composition of a tissue sample from B/A and c measurements.