Story of an Age-Old Reagent: An Electrophilic Chlorination of Arenes and Heterocycles by 1-Chloro-1,2-benziodoxol-3-one
Story of an Age-Old Reagent: An Electrophilic Chlorination of Arenes and Heterocycles by 1-Chloro-1,2-benziodoxol-3-one
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古老试剂的故事：1-Chloro-1,2-benziodoxol-3-one 对芳烃和杂环化合物的亲电氯化
DOI：
10.1021/acs.orglett.6b00547
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发表时间：
2016
期刊：
影响因子：
5.2
通讯作者：
Xiao Jianliang
中科院分区：
文献类型：
--
作者：
Wang Mengzhou;Zhang Yanyan;Wang Tao;Wang Chao;Xue Dong;Xiao Jianliang
By the use of 1-chloro-1,2-benziodoxol-3-one, an age-old reagent, the practical and efficient chlorination method is achieved. This hypervalent iodine reagent is amenable not only to the chlorination of nitrogen-containing heterocycles but also to selected classes of arenes, BODIPY dyes, and pharmaceuticals. In addition, the advantages, such as easy preparation and recyclable, air- and moisture-stable, in combination with the success in a gram-scale experiment grant this reagent great potential for industrial application.
