Statistical methods for analysis of radiation effects with tumor and dose location-specific information with application to the WECARE study of asynchronous contralateral breast cancer.
Statistical methods for analysis of radiation effects with tumor and dose location-specific information with application to the WECARE study of asynchronous contralateral breast cancer.
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DOI：
10.1111/j.1541-0420.2008.01096.x
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发表时间：
2009-06
期刊：
影响因子：
1.9
通讯作者：
Bernstein JL
中科院分区：
文献类型：
--
作者：
Langholz B;Thomas DC;Stovall M;Smith SA;Boice JD Jr;Shore RE;Bernstein L;Lynch CF;Zhang X;Bernstein JL
描述了具有特定位置的辐射剂量和肿瘤位置信息的个体匹配病例对照研究的分析方法。这些方法包括仅使用肿瘤信息精确定位的病例进行分析的似然方法，以及还包括肿瘤位置信息不精确的病例的方法。该理论确立了这些基于似然的方法中的每一种都在位置和受试者水平协变量效应的适当模型的背景下估计相同的辐射率比参数。描述了基本假设，并描述了每种方法的潜在优势和局限性。使用WeCare对放射和非同步对侧乳腺癌的研究对这些方法进行了说明和比较。
Methods for the analysis of individually matched case-control studies with location-specific radiation dose and tumor location information are described. These include likelihood methods for analyses that just use cases with precise location of tumor information and methods that also include cases with imprecise tumor location information. The theory establishes that each of these likelihood based methods estimates the same radiation rate ratio parameters, within the context of the appropriate model for location and subject level covariate effects. The underlying assumptions are characterized and the potential strengths and limitations of each method are described. The methods are illustrated and compared using the WECARE study of radiation and asynchronous contralateral breast cancer.
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影响因子：
158.5
作者：
TUCKER, MA;DANGIO, GJ;FRAUMENI, JF
通讯作者：
FRAUMENI, JF
影响因子：
3.4
作者：
Murley, JS;Kataoka, Y;Grdina, DJ
通讯作者：
Grdina, DJ
DOI：
10.1186/bcr771
发表时间：
2004
期刊：
Breast cancer research : BCR
影响因子：
--
作者：
Bernstein JL;Langholz B;Haile RW;Bernstein L;Thomas DC;Stovall M;Malone KE;Lynch CF;Olsen JH;Anton-Culver H;Shore RE;Boice JD Jr;Berkowitz GS;Gatti RA;Teitelbaum SL;Smith SA;Rosenstein BS;Børresen-Dale AL;Concannon P;Thompson WD;WECARE study
通讯作者：
WECARE study
影响因子：
5
作者：
ARMSTRONG, BG
通讯作者：
ARMSTRONG, BG
影响因子：
120.7
作者：
Travis, LB;Hill, DA;Gilbert, E
通讯作者：
Gilbert, E