Associations between weather conditions and clinical symptoms in patients with hip osteoarthritis: A 2-year cohort study
Associations between weather conditions and clinical symptoms in patients with hip osteoarthritis: A 2-year cohort study
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DOI：
10.1016/j.pain.2014.01.018
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发表时间：
2014-04-01
期刊：
影响因子：
7.4
通讯作者：
Bierma-Zeinstra, Sita M. A.
中科院分区：
文献类型：
--
作者：
Dorleijn, Desiree M. J.;Luijsterburg, Pim A. J.;Bierma-Zeinstra, Sita M. A.
本研究的目的是评估周围天气条件与髋关节骨关节炎（OA）患者的临床症状之间是否存在相关性。研究设计为队列研究，随访2年，测量3个月，前瞻性收集天气变量数据。研究人群包括222例髋关节OA初级保健患者。天气变量包括温度、风速、总日照时数、降水量、气压和相对湿度。主要结局是髋关节疼痛和髋关节残疾的严重程度，采用西安大略和麦克马斯特大学骨关节炎指数（WOMAC）疼痛和功能子量表进行测量。髋关节疼痛和髋关节残疾和天气变量之间的关联进行了评估，使用粗和多变量调整的线性混合模型分析重复测量。在问卷调查完成当天，平均相对湿度与WOMAC疼痛相关（估计值为0.1; 95%置信区间= 0.0-0.2; P = 0.02）。相对湿度贡献
The goal of this study was to assess whether there is an association between ambient weather conditions and patients' clinical symptoms in patients with hip osteoarthritis (OA). The design was a cohort study with a 2-year follow-up and 3-monthly measurements and prospectively collected data on weather variables. The study population consisted of 222 primary care patients with hip OA. Weather variables included temperature, wind speed, total amount of sun hours, precipitation, barometric pressure, and relative humidity. The primary outcomes were severity of hip pain and hip disability as measured with the Western Ontario and McMasters University Osteoarthritis Index (WOMAC) pain and function subscales. Associations between hip pain and hip disability and the weather variables were assessed using crude and multivariate adjusted linear mixed-model analysis for repeated measurements. On the day of questionnaire completion, mean relative humidity was associated with WOMAC pain (estimate 0.1; 95% confidence interval = 0.0-0.2; P =.02). Relative humidity contributed