Experimental glaucoma in the rhesus monkey.
Experimental glaucoma in the rhesus monkey.
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DOI：
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发表时间：
1974-06
期刊：
影响因子：
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通讯作者：
D. Gaasterland;C. Kupfer
中科院分区：
文献类型：
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作者：
D. Gaasterland;C. Kupfer
重复，环形氩激光光凝正常恒河猴前房角的小梁网区域导致持续的眼内压升高和流出设施的显着减少。在本研究的观察期内，视神经乳头出现杯状突起。初步的组织病理学检查显示局部瘢痕的前房角结构。视网膜和视神经的变化，类似于人类慢性开角型青光眼。本文报道了这种实验性青光眼的制备方法。
Repeated, circumferential argon laser photocoagulation of the trabecular meshwork area of the anterior chamber angle of normal Rhesus monkeys causes a sustained elevation of the intraocular pressure and marked reduction of the outflow facility. During the observation period of this study, cupping of the optic nervehead developed. Preliminary histopathologic examination revealed localized scarring of the anterior chamber angle structures. Retinal and optic nerve changes, similar to those seen in human chronic, open-angle glaucoma, were seen. The method to produce this experimental glaucoma is reported.