Waist-to-Height Ratio and Triglycerides/High-Density Lipoprotein Cholesterol Were the Optimal Predictors of Metabolic Syndrome in Uighur Men and Women in Xinjiang, China

Waist-to-Height Ratio and Triglycerides/High-Density Lipoprotein Cholesterol Were the Optimal Predictors of Metabolic Syndrome in Uighur Men and Women in Xinjiang, China
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腰围身高比和甘油三酯/高密度脂蛋白胆固醇是中国新疆维吾尔族男性和女性代谢综合征的最佳预测因子

DOI:
10.1089/met.2014.0146
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发表时间:
2015-06-01
影响因子:
2.1
通讯作者:
Zheng, Ying-Ying
Zheng, Ying-Ying
中科院分区:
医学4区
文献类型:
--
作者:
Chen, Bang-Dang;Yang, Yi-Ning;Zheng, Ying-Ying

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目的:本研究旨在通过比较中国西北部新疆维吾尔族人群中各种人体测量和动脉粥样硬化参数的预测能力,确定代谢综合征的最佳单一预测因子。方法:从2007年10月至2010年3月进行的心血管风险调查(CRS)中总共选取了4767名维吾尔族参与者。人体测量数据、血压、血清总胆固醇(TC)浓度、记录甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)和空腹血糖。代谢综合征及其各个组成部分的患病率根据国际糖尿病联盟 (IDF) 标准进行了确认。比较了代谢综合征存在的每个变量的受试者工作特征曲线下面积(AUC)。计算敏感性(Sen)、特异性(Spe)、受试者工作特征(ROC)曲线中的距离以及每个变量是否存在代谢综合征的截断值。结果:在新疆维吾尔族人群中,总共有 23.7% 的男性患有代谢综合征,而 40.1% 的女性患有代谢综合征;女性代谢综合征患病率显着高于男性(P
Objective: This study aimed to identify the best single predictor of metabolic syndrome by comparing the predictive ability of various anthropometric and atherogenic parameters among a Uighur population in Xinjiang, northwest China.Methods: A total of 4767 Uighur participants were selected from the Cardiovascular Risk Survey (CRS), which was carried out from October, 2007, to March, 2010. Anthropometric data, blood pressure, serum concentration of serum total cholesterol (TC), triglycerides (TGs), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and fasting glucose were documented. Prevalence of metabolic syndrome and its individual components were confirmed according to International Diabetes Federation (IDF) criteria. Area under the receiver operating characteristic curve (AUC) of each variable for the presence of metabolic syndrome was compared. The sensitivity (Sen), specificity (Spe), distance in the receiver operating characteristic (ROC) curve, and cutoffs of each variable for the presence of metabolic syndrome were calculated.Results: In all, 23.7% of men had the metabolic syndrome, whereas 40.1% of women had the metabolic syndrome in a Uighur population in Xinjiang; the prevalence of metabolic syndrome in women was significantly higher than that in men (P