VISUAL LEARNING-DEFICITS IN NONRESECTED PATIENTS WITH RIGHT TEMPORAL-LOBE EPILEPSY
VISUAL LEARNING-DEFICITS IN NONRESECTED PATIENTS WITH RIGHT TEMPORAL-LOBE EPILEPSY
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DOI：
10.1016/s0010-9452(13)80004-4
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发表时间：
1991-12-01
期刊：
影响因子：
3.6
通讯作者：
ELGER, CE
中科院分区：
文献类型：
--
作者：
HELMSTAEDTER, C;POHL, C;ELGER, CE
本文对视觉学习测验诊断Zerebralschizophrenia（DCS）进行了修订，并应用于三组匹配的患者组：24例左颞叶癫痫（LTE），19例右颞叶癫痫（RTE）和34例双颞叶癫痫（BTE）。57名健康志愿者作为对照。对持续注意力和视觉结构的测量也进行了评估。结果如下：（1）与对照组和LTE患者相比，右颞叶癫痫（RTE/BTE）患者的即时回忆率显著降低，学习能力和平均学习成绩也显著降低。(2)患者比对照组犯了更多的错误，RTE患者表现出最多的视觉空间错误。(3)RTE/BTE患者还表现出受损的视觉结构的性能，但当视觉结构分数作为协变量，他们并没有减少学习后的强大的组效应。(4)注意力缺陷独立于记忆缺陷，而反映了癫痫的双颞扩展。因此，本研究结果显示右颞叶癫痫患者的视觉空间整合过程受损。
A visual learning test Diagnostikum fur Zerebralschaden (DCS) was revised and applied to three matched patient groups defined by interictal and ictal EEG findings: 24 patients with left temporal lobe epilepsy (LTE), 19 patients with right temporal lobe epilepsy (RTE) and 34 patients with a bitemporal epileptic involvement (BTE). Fifty seven healthy subjects served as controls. Performance on a measure of sustained attention and visual construction was also assessed. Results were as follows: (1) In contrast to controls and LTE patients, patients with right temporal epileptic involvement (RTE/BTE) showed a significantly reduced immediate recall as well as a reduced learning capacity and mean learning performance. (2) Patients made significantly more errors than controls, with RTE patients exhibiting the most visuo-spatial errors. (3) RTE/BTE patients additionally showed impaired performances on visuoconstruction, but when visual construction scores were used as covariate, they did not diminish the strong group effects upon learning. (4) Attentional deficits were independent from memory deficits and rather reflected the bitemporal extention of epilepsy. As a conclusion, the data suggest an impairment of visual-spatial consolidation processes in patients with right temporal lobe epilepsy.