MR imaging findings in mild traumatic brain injury with persistent neurological impairment
MR imaging findings in mild traumatic brain injury with persistent neurological impairment
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DOI：
10.1016/j.mri.2016.12.009
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发表时间：
2017-04-01
影响因子：
2.5
通讯作者：
Benson, Randall R.
中科院分区：
文献类型：
--
作者：
Trifan, Gabriela;Gattu, Ramtilak;Benson, Randall R.
创伤性脑损伤(TBI)是神经系统残疾的一种普遍原因，70%的病例严重程度较轻。磁共振成像为脑损伤的诊断提供了客观的生物标记物，通过检测创伤引起的脑损伤。本文报道了应用液体衰减反转恢复(FLAIR)和磁化率加权成像(SWI)对有慢性持续性症状的颅脑损伤患者的创伤相关病理的诊断率。方法：由人身伤害律师推荐的180例颅脑损伤后持续神经行为症状的患者和94名无症状、年龄匹配的志愿者参加研究。83%的脑外伤受试者被归类为轻度。结果：颅脑损伤受试者FLAIR发现的病变数目明显多于对照组(42%比22%)，SWI发现的病变比对照组多(28%比3%)。为了减少衰老的混杂影响，我们检查了轻度脑外伤受试者。
Traumatic brain injury (TBI) is a widespread cause of neurologic disability, with >70% of cases being mild in severity. Magnetic resonance imaging provides objective biomarlcers in the diagnosis of brain injury by detecting brain lesions resulting from trauma. This paper reports on the detection rates of presumed trauma related pathology using fluid-attenuated inversion recovery (FLAIR) and susceptibility-weighted imaging (SWI) in TBI patients with chronic, persistent symptoms. Methods: 180 subjects with persistent neurobehavioral symptoms following head trauma referred by personal injury attorneys and 94 asymptomatic, age-matched volunteers were included in the study. 83% of TBI subjects were classified as mild. Results: TBI subjects had a significantly greater number of lesions detected by FLAIR than controls (42% vs. 22%) and more lesions detected by SWI than controls (28% vs. 3%). To reduce the confounding effects of aging, we examined mild TBI subjects