Comprehensive blood coagulation potential in patients with acquired hemophilia A: retrospective analyses of plasma samples obtained from nationwide centers across Japan
Comprehensive blood coagulation potential in patients with acquired hemophilia A: retrospective analyses of plasma samples obtained from nationwide centers across Japan
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DOI：
10.1007/s12185-021-03249-w
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发表时间：
2021-11-01
影响因子：
2.1
通讯作者：
Nogami, Keiji
中科院分区：
文献类型：
--
作者：
Takeyama, Masahiro;Sasai, Kana;Nogami, Keiji
用凝块波形分析(CWA)和/或凝血酶和纤溶酶生成试验对59例获得性血友病A(PwAHA)患者的整体凝血潜能进行了评估。通过与FVIII：C：T1(FVIII：C<；1IU/dL)，T2(1)相关的凝血势分级，比较先天性HA患者凝血因子VIII活性(FVIII：C)与CWA和T/P-GA参数的关系
Global coagulation potential was assessed in 59 patients with acquired hemophilia A (PwAHA) by clot waveform analysis (CWA) and/or thrombin and plasmin generation assay. Relationships between factor VIII activity (FVIII:C) and the parameters from CWA and T/P-GA in patients with congenital HA were compared by grading coagulation potential related to FVIII:C: T1 (FVIII:C < 1 IU/dL), T2 (1