Transcriptome analysis identifies metallothionein as biomarkers to predict recurrence in hepatocellular cacinoma
Transcriptome analysis identifies metallothionein as biomarkers to predict recurrence in hepatocellular cacinoma
复制标题
转录组分析确定金属硫蛋白作为预测肝细胞癌复发的生物标志物
DOI：
10.1002/mgg3.693
复制
发表时间：
2019-06-01
影响因子：
2
通讯作者：
Gribskov，Michael
中科院分区：
文献类型：
--
作者：
Wang，Sufang;Gribskov，Michael
肝癌是第五常见的癌症，肝细胞癌（HCC）是成人中常见的主要肝脏肿瘤类型。HCC通常由慢性肝病如B型肝炎病毒或丙型肝炎病毒感染引起。肝细胞癌的一种有希望的治疗方法是肝移植，其中患病的肝脏被另一个人的健康肝脏所取代。然而，HCC手术后复发是一个重大问题。因此，重要的是要发现可靠的细胞生物标志物，可以预测肝癌复发。
Liver cancer is the fifth most common cancer, and hepatocellular carcinoma (HCC) is the major liver tumor type seen in adults. HCC is usually caused by chronic liver disease such as hepatitis B virus or hepatitis C virus infection. One of the promising treatments for HCC is liver transplantation, in which a diseased liver is replaced with a healthy liver from another person. However, recurrence of HCC after surgery is a significant problem. Therefore, it is important to discover reliable cellular biomarkers that can predict recurrence in HCC.