Variables Influencing Outcome of Helicobacter pylori Eradication Therapy in South China

Variables Influencing Outcome of Helicobacter pylori Eradication Therapy in South China
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华南地区幽门螺杆菌根除治疗效果的影响因素

DOI:
10.1111/j.1523-5378.2009.00718.x
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发表时间:
2009-10-01
期刊:
影响因子:
4.4
通讯作者:
Yu, Min
Yu, Min
中科院分区:
医学2区
文献类型:
--
作者:
Cai, Wenzhi;Zhou, Liping;Yu, Min

文献摘要

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背景:联合使用质子泵抑制剂(PPI)、克拉霉素和阿莫西林或甲硝唑作为治疗幽门螺杆菌感染的一线药物被广泛推荐。本研究的目的是观察含PPI的三联疗法在华南地区的疗效,并找出影响幽门螺杆菌感染治愈率的因素。材料和方法:收集中国南部5省25家医院不同职业的H.他们接受了为期一周的PPI、甲硝唑和阿莫西林三联疗法。根除幽门螺杆菌的评估方法是
Background:Therapy combining a proton pump inhibitor (PPI), clarithromycin and either amoxicillin or metronidazole is widely recommended for first-line treatment for Helicobacter pylori infection. The purpose of this study was to examine the outcomes of PPI-containing triple therapy and identify factors influencing the cure rate of H. pylori infection in South China.Materials and Methods:H. pylori positive patients with different occupations from 25 hospitals in five provinces of South China were enrolled. They received a PPI, metronidazole and amoxicillin triple therapy for a week. H. pylori eradication was evaluated by