Predictive factors for nocturia in elderly men: a cross-sectional study in 21 general practices
Predictive factors for nocturia in elderly men: a cross-sectional study in 21 general practices
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DOI：
10.1111/j.1464-410x.2006.06029.x
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发表时间：
2006-03-01
影响因子：
4.5
通讯作者：
Van Kerrebroeck, PEVA
中科院分区：
文献类型：
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作者：
Gourova, LW;Van de Beek, C;Van Kerrebroeck, PEVA
目的了解夜尿症的患病率，并探讨夜尿症的相关因素。研究对象和方法收集了3048名老年男性的数据，他们填写了一份问卷，并将问卷发送给荷兰马斯特里赫特21家全科诊所的55-75岁男性。夜尿症的症状定义为两次或两次以上的夜间排空。我们调查了夜尿症的患病率及其与以下因素的预测关系：脑血管疾病、糖尿病/尿崩症（DMI）、帕金森病、心血管疾病、高血压、膀胱/前列腺癌、肾脏疾病、膀胱炎症、先天性疾病（肾脏或前列腺）、下尿路症状用药治疗、其他治疗、心理抑郁、良性前列腺增生（BPH）症状提示、酒精摄入。结果对2934名调查对象的数据进行分析；夜尿症（两次或两次以上夜间排空）患病率为32.9%（965名男性）。夜间排尿次数的频率为：588例为0例（20.0%），1344例为1例（45.8%），611例为2例（20.8%），208例为3例（7.1%），70例为4例（2.4%），76例为5例及以上（2.6%），其中37例缺失。多因素logistic回归分析显示，老年男性夜尿症与膀胱/前列腺癌、脑血管疾病、排尿障碍治疗和适度饮酒显著相关。其次，BPH与夜尿症有显著关系，特别是在DMI和高血压的受访者中。心血管疾病或高血压与夜尿症有显著相关性，两者互为替代。结论老年男性夜尿症与早期泌尿系统疾病、心脑血管疾病、BPH、DMI、行为习惯等潜在危险因素有关。其中一些来源可能相互作用，并在某些人群中产生特别高的夜尿症风险。
Objective To measure the prevalence of nocturia in general practice and to determine which factors are associated with nocturia.Subjects and Methods Data were collected from 3048 elderly men, who completed a questionnaire that was sent to every man aged 55-75 years in 21 general practices in Maastricht (the Netherlands). The symptom of nocturia was defined as two or more nocturnal voids. We investigated the prevalence of nocturia and the predictive relationships with the following factors: cerebrovascular disease, diabetes mellitus/insipidus (DMI), Parkinson's diseases, cardiovascular disease, hypertension, bladder/prostate cancer, kidney diseases, urinary bladder inflammation, congenital diseases (kidneys or prostate), using medical treatment for lower urinary tract symptoms, other treatment, psychological depression, symptoms suggestive of benign prostatic hyperplasia (BPH), and alcohol intake.Results Data from 2934 respondents were analysed; the prevalence of nocturia (two or more nocturnal voids) was 32.9% (965 men). The frequency of the number of nocturnal voids was: zero in 588 (20.0%), one in 1344 (45.8%), two in 611 (20.8%), three in 208 (7.1%), four in 70 (2.4%), and five or more in 76 (2.6%), with 37 values missing. A multivariate logistic regression analysis showed that nocturia in elderly men was significantly related to bladder/prostate cancer, cerebrovascular disease, treatment of voiding disorders, and moderate alcohol consumption. Next to these, BPH had a significant relationship with nocturia, especially in respondents with DMI and hypertension. Cardiovascular disease or hypertension was significantly related to nocturia, mutually replacing each other as a risk factor.Conclusion Nocturia in elderly men is be related to many sources of potential risk factors: earlier urological diseases, cardiovascular and cerebrovascular diseases, BPH, DMI and behavioural habits. Some of these sources may interact and generate especially high risk in some groups for nocturia.