Correlation between heart rate variability and haemodynamic fluctuation during induction of general anaesthesia: comparison between linear and non-linear analysis

Correlation between heart rate variability and haemodynamic fluctuation during induction of general anaesthesia: comparison between linear and non-linear analysis
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DOI:
10.1111/j.1365-2044.2006.04933.x
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发表时间:
2007-02-01
期刊:
影响因子:
10.7
通讯作者:
Komatsu, T.
Komatsu, T.
中科院分区:
医学1区
文献类型:
--
作者:
Fujiwara, Y.;Kurokawa, S.;Komatsu, T.

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本研究的目的是比较线性和非线性分析的心率变异性(HRV)的相关性与血流动力学波动在诱导全身麻醉。术前,心率变异性估计MemCalc方法在114例患者计划全身麻醉。异丙酚、芬太尼、维库溴铵诱导后行气管插管。记录麻醉诱导过程中的血流动力学波动,并采用Logistic回归分析研究术前HRV与血流动力学波动之间的相关性。超短时熵(UsEn)作为心率变异性非线性分析的指标,与血压波动的相关性优于心率变异性低频分量功率与高频分量功率之比(LF/HF)。LF/HF与气管插管引起的心率增加显著相关,而UsEn与心率波动相关性不显著。
The objective of this study was to compare linear and non-linear analysis of heart rate variability (HRV) in terms of correlation with haemodynamic fluctuation during induction of general anaesthesia. Pre-operatively, HRV was estimated by the MemCalc method in 114 patients scheduled for general anaesthesia. After anaesthesia was induced with propofol, fentanyl and vecuronium bromide, tracheal intubation was performed. Haemodynamic fluctuations during induction of anaesthesia were recorded and the correlation between pre-operative HRV and haemodynamic fluctuation was examined using logistic regression analysis. As an index of non-linear analysis of HRV, ultra short-term entropy (UsEn) correlated better with blood pressure fluctuation than did the ratio of the power of low frequency component of HRV to that of high frequency component (LF/HF). In contrast, although LF/HF significantly correlated with heart rate increase caused by tracheal intubation, the correlation between UsEn and heart rate fluctuation was not significant.