Endocrine mucin-producing sweat gland carcinoma - A cutaneous neoplasm analogous to solid papillary carcinoma of breast

Endocrine mucin-producing sweat gland carcinoma - A cutaneous neoplasm analogous to solid papillary carcinoma of breast
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DOI:
10.1097/00000478-199712000-00014
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发表时间:
1997-12-01
影响因子:
5.6
通讯作者:
Maluf, HM
Maluf, HM
中科院分区:
医学1区
文献类型:
--
作者:
Flieder, A;Koerner, FC;Maluf, HM

文献摘要

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我们描述了两例独特的原位和侵入性皮肤附属器肿瘤发生在眼睑。粘液癌代表了一个病例中肿瘤的浸润部分,而另一个则浸润在小的实性巢中。原位癌与最近描述的乳腺实性乳头状癌(内分泌导管原位癌)相同。这两个肿瘤产生内和细胞外粘蛋白,表现出内分泌分化的免疫组织化学和超微结构分析,雌激素和孕激素受体阳性。
We describe two cases of a distinctive in situ and invasive cutaneous adnexal neoplasm occurring in the eyelid. Mucinous carcinoma represented the invasive portion of the tumor in one case, whereas the other infiltrated in small solid nests. The in situ component is identical to the recently described solid papillary carcinoma of the breast (endocrine ductal carcinoma in situ). Both tumors produced intra-and extracellular mucin, exhibited endocrine differentiation by immunohistochemistry and ultrastructural analysis, and were positive for estrogen and progesterone receptors.