Initial Clinical Evaluation of an Intraocular Femtosecond Laser in Cataract Surgery
Initial Clinical Evaluation of an Intraocular Femtosecond Laser in Cataract Surgery
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DOI：
10.3928/1081597x-20091117-04
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发表时间：
2009-12-01
影响因子：
2.4
通讯作者：
Sarayba, Melvin
中科院分区：
文献类型：
--
作者：
Nagy, Zoltan;Takacs, Agnes;Sarayba, Melvin
目得：评价飞秒激光透镜破碎术和前囊切开术在白内障手术中的应用。方法：首先在离体猪眼中评价使用眼内飞秒激光（LenSx Lasers Inc）进行的前囊切开术和晶状体破碎术。这些程序，然后进行了初步系列的9例患者接受术中白内障手术。除了标准的评估（包括囊切开术直径的准确性和再现性），光学相干断层扫描被用来评估人类proceeds.Results：对于预期的5毫米撕囊术在猪眼中，平均达到的直径为5.88 +/- 0.73毫米，使用标准的手动技术和5.02 +/- 0.04毫米，使用飞秒激光。扫描电子显微镜显示飞秒激光和手动技术的囊切开术切割边缘同样光滑。与对照猪眼相比，飞秒激光超声乳化碎核术导致超声乳化功率降低43%，超声乳化时间缩短51%。在一个小系列的人类临床程序中，激光囊切开术和超声乳化碎核术表现出同样高水平的准确性和有效性，没有手术并发症。结论：初步结果与眼内飞秒激光证明更高的精度capsulorrhexis和减少超声乳化功率在猪和人的眼睛。[J Refract Surg.2009;25：1053-1060.] doi：10.3928/1081597X-20091117-04
PURPOSE: To evaluate femtosecond laser lens fragmentation and anterior capsulotomy in cataract surgery.METHODS: Anterior capsulotomy and phacofragmentation procedures performed with an intraocular femtosecond laser (LenSx Lasers Inc) were initially evaluated in ex vivo porcine eyes. These procedures were then performed in an initial series of nine patients undergoing intraoperative cataract surgery. In addition to standard assessments (including capsulotomy diameter accuracy and reproducibility), optical coherence tomography was used to evaluate human procedures.RESULTS: For an intended 5-mm capsulorrhexis in porcine eyes, average achieved diameters were 5.88 +/- 0.73 mm using a standard manual technique and 5.02 +/- 0.04 mm using the femtosecond laser. Scanning electron microscopy revealed equally smooth cut edges of the capsulotomy with the femtosecond laser and manual technique. Compared to control porcine eyes, femtosecond laser phacofragmentation resulted in a 43% reduction in phacoemulsification power and a 51% decrease in phacoemulsification time. In a small series of human clinical procedures, laser capsulotomies and phacofragmentation demonstrated similarly high levels of accuracy and effectiveness, with no operative complications.CONCLUSIONS: Initial results with an intraocular femtosecond laser demonstrate higher precision of capsulorrhexis and reduced phacoemulsification power in porcine and human eyes. [J Refract Surg. 2009;25:1053-1060.] doi:10.3928/1081597X-20091117-04