The different hemolysins of Escherichia coli
The different hemolysins of Escherichia coli
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大肠杆菌的不同溶血素
DOI：
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发表时间：
2004
期刊：
影响因子：
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通讯作者：
L. Beutin
中科院分区：
文献类型：
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作者：
L. Beutin
1903年，Kayser首次描述了某些大肠杆菌菌株溶解不同哺乳动物物种红细胞的能力（溶血）。在大肠杆菌培养液中检测到溶血活性。大肠杆菌，分离自人类脓肿和粪便材料。首次报道了溶血素的产生与人类尿路感染（UTI）的关系。大肠杆菌的研究发表于20世纪20年代初（Dudgeon et al.1921; Dudgeon et al.1922）。从那时起，E.大肠杆菌的生物学和生化特性及其作为大肠杆菌毒力因子的意义。人类和动物的大肠杆菌感染。本文对E.大肠杆菌的特性及其在致病性中的作用。
The ability of certain strains of Escherichia coli to lyse erythrocytes of different mammalian species (hemolysis) was first described by Kayser in 1903. The hemolytic activity was detected in the culture fluid of E. coli which were isolated from human abcesses and from fecal material. First reports on the association of hemolysin production with urinary tract infection (UTI) in humans by E. coli were published in the early twenties (Dudgeon et al. 1921; Dudgeon et al. 1922). Since that time the hemolysins of E. coli have been investigated mainly for two aspects: their biological and biochemical properties and their significance as virulence factors in E. coli infections of humans and animals. The purpose of this work is to present an overview on the different hemolysins described in E. coli and the state of knowledge on their properties and their role in pathogenicity.