DNA repair and the role of chromatin structure.

DNA repair and the role of chromatin structure.
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DOI:
10.1016/0955-0674(91)90069-b
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发表时间:
1991-06
影响因子:
7.5
通讯作者:
M. Smerdon
M. Smerdon
中科院分区:
生物学2区
文献类型:
--
作者:
M. Smerdon

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1990 年,酵母微小染色体特定位点的可变修复效率的证明以及人类神经退行性疾病中缺乏基因特异性修复是亮点之一,当时许多报告都强调了染色质结构在 DNA 损伤形成及其后续修复中的重要作用。
The demonstration of variable repair efficiency at specific sites in a yeast minichromosome and the lack of gene-specific repair in a human neurodegenerative disorder were among the highlights in 1990, when many reports emphasized the significant role of chromatin structure in both DNA damage formation and its subsequent repair.