Differential impairment of individuated finger movements in humans after damage to the motor cortex or the corticospinal tract
Differential impairment of individuated finger movements in humans after damage to the motor cortex or the corticospinal tract
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DOI：
10.1152/jn.00130.2003
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发表时间：
2003-08-01
影响因子：
2.5
通讯作者：
Schieber, MH
中科院分区：
文献类型：
--
作者：
Lang, CE;Schieber, MH
本研究的目的是量化病变相对局限于运动皮层或皮质脊髓束的人类独立手指运动的长期丧失。我们质疑运动皮层或皮质脊髓束的损伤是否会永久影响每个手指相同程度移动的能力，或者是否会比其他手指对某些手指的影响更大。以缺血性脑血管意外导致的单纯运动性偏瘫患者作为实验样本。测试纯运动性偏瘫和对照受试者独立进行每个手指的周期性屈曲/伸展运动的能力。我们使用仪器手套记录了他们的手指关节运动。对照受试者和偏瘫受试者未受影响的手（病变同侧）的手指相对独立地移动。偏瘫受试者受影响的手（病变对侧）的手指独立手指运动的能力受到不同程度的损害。拇指独立性正常；食指的独立性受到轻微损害，而中指、无名指和小指的独立性受到严重损害。运动皮质或皮质脊髓损伤对手指独立性的不同长期影响可能是由于康复训练强调需要独立拇指和食指运动的任务，以及与其他四个手指相比，神经肌肉系统的备用部分独立控制拇指的能力更强。
The purpose of this study was to quantify the long-term loss of independent finger movements in humans with lesions relatively restricted to motor cortex or corticospinal tract. We questioned whether damage to the motor cortex or corticospinal tract would permanently affect the ability to move each finger to the same degree or would affect some fingers more than others. People with pure motor hemiparesis due to ischemic cerebrovascular accident were used as our experimental sample. Pure motor hemiparetic and control subjects were tested for their ability to make cyclic flexion/extension movements of each finger independently. We recorded their finger joint motion using an instrumented glove. The fingers of control subjects and of the unaffected hands ( ipsilateral to the lesion) of hemiparetic subjects moved relatively independently. The fingers of the affected hands ( contralateral to the lesion) of hemiparetic subjects were differentially impaired in their ability to make independent finger movements. The independence of the thumb was normal; the independence of the index finger was slightly impaired, while the independence of the middle, ring, and little fingers was substantially impaired. The differential long-term effects of motor cortical or corticospinal damage on finger independence may result from rehabilitative training emphasizing tasks requiring independent thumb and index movements, and from a greater ability of the spared components of the neuromuscular system to control the thumb independently compared with the other four fingers.