Cognitive Frailty is Associated with Fall-Related Fracture among Older People
Cognitive Frailty is Associated with Fall-Related Fracture among Older People
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DOI：
10.1007/s12603-018-1131-4
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发表时间：
2018-12-01
影响因子：
5.8
通讯作者：
Shimada, H.
中科院分区：
文献类型：
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作者：
Tsutsumimoto, K.;Doi, T.;Shimada, H.
目的认知衰弱是指认知障碍和身体衰弱。认知障碍和身体虚弱都包括跌倒的风险。该研究的目的是检查认知衰弱和跌倒（有/无骨折）。设计横断面观察研究。设置日本一般社区。参与者收集了 10,202 名 65 岁老年人的数据。测量身体虚弱的特征是步行速度慢和/或肌肉无力。认知功能评估包括单词列表记忆、注意力、执行功能和处理速度。认知障碍是指在调整年龄和教育程度后，表现为低于阈值至少 1.5 个标准差的一种或多种认知能力下降。我们在操作上将认知脆弱定义为同时具有认知障碍和身体脆弱。受访者接受了关于跌倒、跌倒相关骨折史以及人口统计学特征等一些潜在混杂因素的采访。结果多项逻辑回归分析显示，在调整协变量后，与健壮组相比，所有组的功能下降与无骨折跌倒显着相关；认知障碍组 (P =.017)、身体虚弱组 (P =.002) 和认知虚弱组 (P =.002)
ObjectiveCognitive frailty refers to cognitive impairment and physical frailty. Both cognitive impairment and physical frailty include risks of falling. The purpose of the study is to examine cognitive frailty and falling with/without a fracture.DesignCross-sectional observation study.SettingGeneral communities in Japan.ParticipantsData of 10,202 older adults aged 65 years were collected.MeasurementsPhysical frailty was characterized as slow walking speed and/or muscle weakness. Assessment of cognitive function included word lists memory, attention, executive function, and processing speed. Cognitive impairment refers to one or more cognitive decline indicated by at least 1.5 standard deviations below the threshold after adjusting for age and education. We operationally defined cognitive frailty as having both cognitive impairment and physical frailty. Participants were interviewed about their falling, history of fall-related fractures, and several potentially confounding factors such as demographic characteristics.ResultsMultinomial logistic regression analysis revealed that functional decline in all groups, as compared to the robust group, was significantly associated with falling without fractures, after adjusting for the covariates; cognitive impairment group (P =.017), physical frailty group (P =.002), and cognitive frailty group (P