Objective sleep in pediatric anxiety disorders and major depressive disorder
Objective sleep in pediatric anxiety disorders and major depressive disorder
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DOI：
10.1097/chi.0b013e31815cd9bc
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发表时间：
2008-02-01
影响因子：
13.3
通讯作者：
Dahl, Ronald E.
中科院分区：
文献类型：
--
作者：
Forbes, Erika E.;Bertocci, Michele A.;Dahl, Ronald E.
目的：探讨早发性焦虑和抑郁患者的客观和主观睡眠问题。方法：患有焦虑症（n = 24）、无焦虑症共病的重度抑郁症（MDD）（n = 128）或无精神疾病史（n = 101）的儿童和青少年（46%为女性，年龄7至17岁）在睡眠实验室连续两晚，并完成睡眠质量的自我报告。结果如下：在客观指标上，焦虑组比MDD组有更多的觉醒，慢波睡眠比对照组或MDD组少，第2夜睡眠潜伏期比MDD组或对照组长。焦虑组从第一晚到第二晚的快速眼动潜伏期没有减少。MDD组的清醒时间少于对照组，第1阶段睡眠少于焦虑组或对照组。在主观测量方面，患有焦虑症的年轻人在第二天晚上的睡眠潜伏期更长，睡眠潜伏期没有减少。年龄在分析中是协变的。结论：研究结果提供了儿童和青少年焦虑症患者睡眠障碍的客观和主观证据，并在MDD患者中复制了有限的客观睡眠障碍的结果。睡眠问题是治疗年轻人焦虑时的重要考虑因素。
Objective: To examine objective and subjective sleep problems in early-onset anxiety and depression. Method: Children and adolescents (46% female, ages 7 to 17 years) with anxiety disorders (n = 24), major depressive disorder (MDD) without comorbid anxiety disorders (n = 128), or no history of psychiatric disorder (n = 101) spent two consecutive nights in a sleep laboratory and completed self-reports of sleep quality. Results: On objective measures, the anxiety group exhibited more awakenings than the MDD group, less slow-wave sleep than the control or MDD group, and greater night 2 sleep latency than the MDD or control group. The anxiety group exhibited no decrease in rapid eye movement latency from the first night to the second. The MDD group exhibited less time awake than the control group and less stage 1 sleep than the anxiety or control group. On subjective measures, young people with anxiety reported greater sleep latency on the second night and no decrease in sleep latency. Age was covaried in analyses. Conclusions: Findings provide objective and subjective evidence of sleep disturbance in children and adolescents with anxiety disorders and replicate findings of limited objective sleep disturbance in those with MDD. Sleep problems are an important consideration when treating young people with anxiety.