Synthesis of mesoporous multiwall ZnO nanotubes by replicating silk and application for enzymatic biosensor.
Synthesis of mesoporous multiwall ZnO nanotubes by replicating silk and application for enzymatic biosensor.
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DOI：
10.1016/j.bios.2013.05.017
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发表时间：
2013-11
影响因子：
12.6
通讯作者：
Minggang Zhao;Zhenglong Li;Ziqi Han;Ke Wang;Yu Zhou;Jingyun Huang;Z. Ye
中科院分区：
文献类型：
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作者：
Minggang Zhao;Zhenglong Li;Ziqi Han;Ke Wang;Yu Zhou;Jingyun Huang;Z. Ye
提出了一种用于制造介孔多壁氧化锌纳米管（ZnO-MMNT）的面部生物模板导向合成路线。由于基于介孔多壁的基质、基于一维（1D）管的通道和高等电点（IEP），所制备的ZnO-MMNT是固定葡萄糖氧化酶（GOx）用于葡萄糖生物传感的绝佳平台。规模适应性细胞的构造是为了容纳酶分子、维持酶活性并保持稳定性。制备的酶电极（壳聚糖/GOx/ZnO/Au）具有高灵敏度（47.2 μA mM− 1 cm− 2）、非常快的响应（< 2 s）、相当低的K M a p p（1.09 mM）、优异的选择性和稳定性。因此，ZnO-MMNT 是用于酶组装和其他生物应用的有前途的材料。
A facial biotemplate-directed synthetic route for fabricating mesoporous multiwall ZnO nanotubes (ZnO-MMNTs) was proposed. Owing to the mesoporous multiwall based matrix, one dimensional (1D) tubes based channels and high isoelectric point (IEP), the prepared ZnO-MMNTs are wonderful platform to immobilize glucose oxidase (GOx) for glucose biosensing. Scale-adaptive cells are constructed to hold enzymes molecules, maintain enzymatic activity and keep stability. The prepared enzymatic electrode (chitosan/GOx/ZnO/Au) exhibits high sensitivity (47.2 μA mM− 1 cm− 2), very fast response (< 2 s), quite low K M a p p (1.09 mM), excellent selectivity and stability. Therefore, ZnO-MMNTs are promising material for enzyme assembly and other biological applications.