GENE CONVERSION BETWEEN DUPLICATED GENETIC ELEMENTS IN YEAST
GENE CONVERSION BETWEEN DUPLICATED GENETIC ELEMENTS IN YEAST
复制标题
DOI：
10.1038/292306a0
复制
发表时间：
1981-01-01
期刊：
影响因子：
64.8
通讯作者：
FINK, GR
中科院分区：
文献类型：
--
作者：
JACKSON, JA;FINK, GR
研究了酵母S.酿酒厂进行了研究。重复片段之间的主要重组事件是与相互重组无关的基因转换。rad 52 -1突变优先减少有丝分裂基因转换。有丝分裂基因转换可能通过与减数分裂不同的途径发生。这种有丝分裂的基因转换可能是重要的酵母交配型相互转换和维持序列的同质性在家庭中的重复真核基因。
The mitotic recombination behavior of a duplication of the his4 region on chromosome III in the yeast S. cerevisiae was studied. The major recombination event between the duplicated segments is gene conversion unassociated with reciprocal recombination. The rad52-1 mutation preferentially decreases mitotic gene conversion. Mitotic gene conversion may occur by a different pathway from that occurring in meiosis. This mitotic gene conversion may be important in yeast mating type interconversion and maintenance of sequence homogeneity in families of repeated eukaryotic genes.