Contact angle changes induced by immunocomplex formation
Contact angle changes induced by immunocomplex formation
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DOI：
10.1039/c3an02189k
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发表时间：
2014-01-01
期刊：
影响因子：
4.2
通讯作者：
Chung, Jae-Hyun
中科院分区：
文献类型：
--
作者：
Kim, Jong-Hoon;Shen, Amy Q.;Chung, Jae-Hyun
分析抗原和抗体之间相互作用的免疫测定可受到毛细管作用以及结合亲和力的影响。本文研究了细菌悬液在抗体固定表面上接触角的变化。毛细管作用和细菌悬浮液的干燥模式进行了分析，并与细菌和抗体之间的特异性和非特异性结合。
Immunoassays analyzing interactions between antigens and antibodies can be affected by capillary action together with binding affinity. This paper studies contact-angle changes of bacterial suspensions on antibody immobilized surfaces. The capillary action and the dried pattern of the bacterial suspensions are analyzed and correlated with specific- and nonspecific bindings between bacteria and antibodies.