Syntheses of aladan and [Ald6]loloatin C and study on their fluorescent properties
Syntheses of aladan and [Ald6]loloatin C and study on their fluorescent properties
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DOI：
10.1002/cjoc.200690264
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发表时间：
2006-10-01
影响因子：
5.4
通讯作者：
Zhong Xian-Bin
中科院分区：
文献类型：
--
作者：
Chen He-Ru;Guo Xi-Kun;Zhong Xian-Bin
合成了β-[6 ′-（N，N ′-二甲基）氨基-2 ′-萘甲酰基]丙氨酸（Aladan）和含Aladan的环十肽[Ald（6）]-loloatin C。进一步研究了它们在水性缓冲液以及十二烷基硫酸钠（SDS）和十二烷基磷酸胆碱（DPC）形成的胶束中的荧光行为。结果表明，在两种胶束体系中，[Ald（6）]loloatin C均具有红移的最大发射波长和较高的量子产率。这一特性可用于研究多肽与细胞膜的相互作用。
Aladan (beta-[6'-(NN,-dimethyl)amino-2'-naphthoyl]alanine) and aladan-containing cyclodecapeptide [Ald(6)]-loloatin C were synthesized. The properties of their fluorescent behaviours both in aqueous buffer and micelles created by sodium dodecylsulfate (SDS) and dodecylphosphorylcholine (DPC) were further investigated. It was found that in either of micelle systems, [Ald(6)]loloatin C possesses red-shift emission maximum wavelength and higher quantum yield. This property could be useful in the research of peptide-cell membrane interaction.