The prognostic significance of weight loss and its integration in stage-grouping of oesophageal cancer.
The prognostic significance of weight loss and its integration in stage-grouping of oesophageal cancer.
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体重减轻的预后意义及其在食管癌分期中的整合。
DOI：
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发表时间：
1982
期刊：
影响因子：
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通讯作者：
J. Lober
中科院分区：
文献类型：
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作者：
H. Pedersen;Hansen Hs;C. Cederqvist;J. Lober
166 名食道癌患者根据体重减轻分为两组。体重减轻小于或等于 10% 的患者的生存期明显长于体重减轻大于 10% 的患者。在体重减轻小于或等于 10% 的组中，最初身体状况不佳的患者通过肠外营养改善后的情况与自发状况良好的患者一样。 159 可以根据 UICC 分类进行阶段分组。这种分类没有给出关于生存的明确分层。如果在将 UICC 分期与体重减轻程度相结合的系统中将患者重新分为三个阶段，则可以获得各个阶段之间生存率的显着差异。建议将体重减轻程度纳入食管癌分期。
166 patients suffering from oesophageal cancer were subdivided into two groups with respect to weight loss. Survival of patients with less than or equal to 10% weight loss was significantly longer than in patients with greater 10% weight loss. Within the group with less than or equal 10% weight loss, patients in initial poor physical condition who improved on parenteral nutrition did as well as those in a spontaneously good condition. 159 could be stage-grouped according to the UICC classification. This classification did not give a clear-cut stratification with respect to survival. If the patients were reclassified into three stages in a system combining UICC stages with degree of weight loss, significant differences in survival between the individual stages could be obtained. It is recommended that the degree of weight loss is integrated in the stage-grouping of oesophageal cancer.