Genome-wide association study reveals the genetic architecture of 27 agronomic traits in tomato
Genome-wide association study reveals the genetic architecture of 27 agronomic traits in tomato
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全基因组关联研究揭示了番茄 27 个农艺性状的遗传结构
DOI：
10.1093/plphys/kiab230
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发表时间：
2021
期刊：
影响因子：
7.4
通讯作者：
Ye Zhibiao
中科院分区：
文献类型：
--
作者：
Ye Jie;Wang Xin;Wang Wenqian;Yu Huiyang;Ai Guo;Li Changxing;Sun Pengya;Wang Xianyu;Li Hanxia;Ouyang Bo;Zhang Junhong;Zhang Yuyang;Han Heyou;Giovannoni James J.;Fei Zhangjun;Ye Zhibiao
番茄（Solanum lycopersicum）是一种重要的水果作物，产量是其重要的农艺性状之一。然而，番茄产量相关性状的遗传结构尚未完全解决。基于从605份不同材料中获得的1440万个单核苷酸多态性，我们对番茄的27个农艺性状进行了全面的全基因组关联研究。共鉴定出239个显著相关的基因，对应于129个基因座，包含许多先前报道的和额外的营养和生殖发育相关的基因，这些基因座平均解释表型方差的1.88%。在番茄的驯化和改良过程中，共选择了与25个性状相关的51个位点。此外，一个候选基因，S1-激活的苹果酸转运蛋白15，编码铝激活的苹果酸转运蛋白的功能特征，并显示作为一个关键的调节器的叶片气孔形成，从而影响光合作用和抗旱性。本研究为番茄遗传研究和育种提供了有价值的信息。
Tomato (Solanum lycopersicum) is a highly valuable fruit crop, and yield is one of the most important agronomic traits. However, the genetic architecture underlying tomato yield-related traits has not been fully addressed. Based on ∼4.4 million single nucleotide polymorphisms obtained from 605 diverse accessions, we performed a comprehensive genome-wide association study for 27 agronomic traits in tomato. A total of 239 significant associations corresponding to 129 loci, harboring many previously reported and additional genes related to vegetative and reproductive development, were identified, and these loci explained an average of ∼8.8% of the phenotypic variance. A total of 51 loci associated with 25 traits have been under selection during tomato domestication and improvement. Furthermore, a candidate gene,Sl-ACTIVATED MALATE TRANSPORTER15, that encodes an aluminum-activated malate transporter was functionally characterized and shown to act as a pivotal regulator of leaf stomata formation, thereby affecting photosynthesis and drought resistance. This study provides valuable information for tomato genetic research and breeding.