Efficacy of percutaneous radiofrequency ablation of osteoid osteoma in children
Efficacy of percutaneous radiofrequency ablation of osteoid osteoma in children
复制标题
DOI：
10.1007/s00247-007-0690-z
复制
发表时间：
2008-02-01
影响因子：
2.3
通讯作者：
Moghazi, Khaled
中科院分区：
文献类型：
--
作者：
Donkol, Ragab H.;Al-Nammi, Ahmed;Moghazi, Khaled
背景：经皮射频消融治疗类骨瘤具有很高的技术和临床成功率。然而，它在治疗儿童类骨瘤中的应用数据有限。目的评估ct引导下经皮射频消融治疗儿童骨样骨瘤的安全性和有效性，并将其与已发表的未经年龄选择的患者的结果进行比较。材料与方法自2003年1月至2006年7月，对23例儿童类骨性骨瘤采用直刚性电极ct引导射频消融治疗。平均年龄11岁（3.5 ~ 16岁），男15例，女8例。手术是在全身麻醉下进行的。随访以评估技术和临床结果。平均随访时间为2.5年（13-49个月）。结果技术成功率21例（91.3%）。两名患儿手术失败，其中一名患儿因未能在致密硬化内充分定位病灶，另一名患儿因出现高热，消融时间较短（2分钟）。18例患者在2 ~ 5天内获得临床成功，初步临床成功率78.2%。术后1周，这些患者可以完全负重和正常活动。2例患者出现疼痛复发；其中1例在6个月后成功进行了第二次消融治疗（二次临床成功率为82.6%）。在手术过程中观察到两例患者体温过高。观察到其他三个轻微并发症：1例儿童伤口感染，2例儿童皮肤烧伤。没有观察到重大的即时或延迟并发症。结论经皮ct引导射频消融治疗儿童类骨瘤是一种安全有效的微创治疗方法。它具有很高的技术和临床成功率，略低于年龄范围更广的患者。
Background Percutaneous radiofrequency (RF) ablation of osteoid osteoma has high technical and clinical success rates. However, there are limited data on its use in the treatment of osteoid osteoma in children.Objective To assess the safety and efficacy of CT-guided percutaneous RF ablation of osteoid osteoma in children and compare the outcomes with published data on its use in patients unselected for age.Materials and methods From January 2003 to July 2006, 23 children with osteoid osteoma were treated with CT-guided RF ablation using a straight rigid electrode. Their mean age was 11 years (range 3.5-16 years) and there were 15 boys and 8 girls. The procedures were carried out under general anaesthesia. Follow-up was performed to assess technical and clinical outcome. The mean follow-up period was 2.5 years (range 13-49 months).Results Technical success was achieved in 21 children (91.3%). Failure occurred in two children, in one due to failure to adequately localize the nidus within the dense sclerosis and in the other because of a short ablation time (2 min) because he developed hyperthermia. Clinical success was achieved in 18 patients within 2-5 days (primary clinical success rate 78.2%).These patients were allowed to fully weight-bear and function without limitation 1 week after the procedure. Pain recurrence was observed in two patients; one was treated successfully with a second ablation after 6 months (secondary clinical success rate 82.6%). Hyperthermia was observed in two patients during the procedure. Three other minor complications were observed: wound infection in one child and skin burn in two children. No major immediate or delayed complications were observed.Conclusion Percutaneous CT-guided RF ablation is an effective and safe minimally invasive procedure for the treatment of osteoid osteoma in children. It has high technical and clinical success rates that are slightly lower than those of patients with a wider range of ages.