Infection and preterm birth
Infection and preterm birth
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DOI:
10.1016/j.siny.2015.12.008
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发表时间:
2016-04-01
影响因子:
3
通讯作者:
Andrews, William W.
中科院分区:
文献类型:
--
作者:
Nadeau, Hugh C. G.;Subramaniam, Akila;Andrews, William W.
Preterm birth (PTB) remains a primary cause of neonatal morbidity and mortality. The purpose of this article is to outline the association between infection and PTB. We performed a search of the PubMed database for relevant scientific work published in English from 1995 to July 2015. Whereas there is substantial evidence regarding infection as a strong risk factor for preterm birth, the role of specific bacterial and viral infections is not totally conclusive. Newer high-dimensional biological technologies such as microbiomics and metabolomics offer hope to identify the causative pathogens. In addition, strategies have been developed to reduce (C) 2015 Elsevier Ltd. All rights reserved.