LIPOPROTEIN-LIPASE ACTIVITY IN HUMAN SKELETAL-MUSCLE AND ADIPOSE-TISSUE IN FASTING AND FED STATES
LIPOPROTEIN-LIPASE ACTIVITY IN HUMAN SKELETAL-MUSCLE AND ADIPOSE-TISSUE IN FASTING AND FED STATES
复制标题
DOI：
10.1016/0021-9150(78)90155-7
复制
发表时间：
1978-01-01
期刊：
影响因子：
5.3
通讯作者：
VESSBY, B
中科院分区：
文献类型：
--
作者：
LITHELL, H;BOBERG, J;VESSBY, B
健康受试者，7名女性和9名男性，平均年龄为25岁（范围22-29岁），在早餐、午餐和2顿小餐后的早晨和8小时后空腹状态下进行研究。脂肪组织中的脂蛋白[脂肪酸]-脂肪酶活性从80 . ±. 32到117 .+-. 61 nmol脂肪酸释放/g和分钟（nmol FA[脂肪酸]/g/分钟）;在腹肌组织中，其从25 ± 10显著降低。11到17 .+-.血清甘油三酯的浓度从0.93 ± 0.9 nmol FA/g/min显著增加。0.18 mmol/l（平均值±. SD）至1.57 . ±. 0.64 mmol/l，在进食状态下。空腹状态下，骨骼肌脂蛋白脂酶活性与胰岛素和胰高血糖素浓度之比呈负相关。
Healthy subjects, 7 females and 9 males, with a mean age of 25 yr (range 22-29 yr), were studied in the fasting state in the morning and 8 h later after partaking of breakfast, lunch and 2 small meals. The lipoprotein[fatty acid]-lipase activity in the adipose tissue increased significantly from 80 .+-. 32 to 117 .+-. 61 nmol fatty acid released/g and minute (nmol FA[fatty acid]/g per min); in skeletal-muscle tissue it decreased significantly from 25 .+-. 11 to 17 .+-. 9 nmol FA/g per min. The concentration of serum triglycerides increased significantly from 0.93 .+-. 0.18 mmol/l (mean .+-. SD) in the fasting state to 1.57 .+-. 0.64 mmol/l in the fed state. In the fasting state the lipoprotein-lipase activity of skeletal msucle was inversely related to the ratio between the concentrations of insulin and glucagon.