Electron microscopy of the pacinian corpuscle.
Electron microscopy of the pacinian corpuscle.
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DOI：
10.1083/jcb.3.3.331
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发表时间：
1957-05-25
期刊：
影响因子：
--
通讯作者：
QUILLIAM TA
中科院分区：
文献类型：
--
作者：
PEASE DC;QUILLIAM TA
太平洋小体的胞质片层在外区呈同心排列，在核区呈双侧排列。在这两者之间是中间生长区。内核显示出一种意想不到的复杂性，它的组成片被排列在两个对称的嵌套细胞质片组中。纵向组织空间形成裂缝，将两组分开。核心层的核周位于中间生长带或其附近，并向裂缝中伸出臂。然后，臂分支并终止为与邻近细胞相交叉的片层。单个神经纤维在到达内核之前失去髓鞘，但保留了一小段额外的雪旺细胞质覆盖物。雪旺鞘与内核的片层不连续。在核心内部，纤维包含一个引人注目的由径向排列的线粒体组成的圆周栅栏。纤维不弯曲。血管毛细血管穿过小体的门区，仅延伸至神经髓鞘，在小体的其他部位未见。在核心间隙和毛细血管附近的组织间隙之间有直接的连续性。这可能提供了一条途径，代谢物由此到达活跃的神经末梢，以及生长区的细胞。外区由至少30个扁平的同心细胞质片片组成，由相对较宽的充满液体的空间彼此隔开。胶原原纤维存在，特别是在薄片的外表面，并倾向于圆形取向。构成生长带的增殖细胞带，在幼小动物的小体中很突出，是形成外片的层。渗透力可能提升了薄片，并维持了膨胀压力。
The Pacinian corpuscle has a framework of cytoplasmic lamellae arranged concentrically in the outer zone, and bilaterally in the core. Between these is an intermediate growth zone. The inner core shows an unexpected complexity in that its component lamellae are arranged in two symmetrical groups of nested cytoplasmic sheets. Longitudinal tissue spaces form clefts separating the two groups. The perikarya of the core lamellae lie in or near the intermediate growth zone, and send arms into the clefts. The arms then branch and terminate as lamellae which interdigitate with those of neighboring cells. The single nerve fiber loses its myelin sheath just before it reaches the inner core but retains its Schwann cell cytoplasmic covering for a short additional distance. The Schwann sheath is not continuous with the lamellae of the inner core. Inside the core the fiber contains a striking circumferential palisade of radially disposed mitochondria. The fiber does not arborize. Vascular capillaries penetrate the hilar region of the corpuscle only as far as the myelinated sheath of the nerve, and they have not been seen elsewhere in the corpuscle. There is direct continuity between the clefts of the core and tissue spaces in the vicinity of the capillaries. It is likely that this provides a route whereby metabolites reach the active nerve ending, as well as the cells of the growth zone. The outer zone consists of at least 30 flattened concentric cytoplasmic lamellae separated from one another by relatively wide fluid-filled spaces. Collagenous fibrils are present, particularly on the outer surface of lamellae, and tend to be oriented circularly. The girdle of proliferating cells constituting the growth zone, which is prominent in corpuscles from young animals, is the layer from which the outer lamellae are derived. Osmotic forces probably elevate the lamellae, and maintain turgor pressure.