Convergence of Humans, Bats, Trees, and Culture in Nipah Virus Transmission, Bangladesh
Convergence of Humans, Bats, Trees, and Culture in Nipah Virus Transmission, Bangladesh
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DOI：
10.3201/eid2309.161922
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发表时间：
2017-09-01
影响因子：
11.8
通讯作者：
Luby, Stephen P.
中科院分区：
文献类型：
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作者：
Gurley, Emily S.;Hegde, Sonia T.;Luby, Stephen P.
预防新的人畜共患病病毒的出现取决于对人类风险决定因素的理解。尼帕病毒（NiV）是一种致命的人畜共患病原体，从蝙蝠传播到人类，人与人之间的传播有限。我们研究了孟加拉国NiV感染风险的地理变异的生态和人类行为驱动因素。我们在2011-2013年期间访问了60个村庄，其中发现了NiV感染病例，并访问了147个对照村庄。我们比较了病例村与对照村的感染风险最可能的驱动因素，包括蝙蝠，人，椰枣树和人类椰枣汁消费行为的数量。案例村在许多方面与对照村相似，包括蝙蝠数量、人员数量和椰枣树汁树，但有人喝椰枣汁的家庭比例较高。减少人类对树液的消费可以减少病毒传播和出现更高传播性的NiV毒株的风险。
Preventing emergence of new zoonotic viruses depends on understanding determinants for human risk. Nipah virus (NiV) is a lethal zoonotic pathogen that has spilled over from bats into human populations, with limited person-to-person transmission. We examined ecologic and human behavioral drivers of geographic variation for risk of NiV infection in Bangladesh. We visited 60 villages during 2011-2013 where cases of infection with NiV were identified and 147 control villages. We compared case villages with control villages for most likely drivers for risk of infection, including number of bats, persons, and date palm sap trees, and human date palm sap consumption behavior. Case villages were similar to control villages in many ways, including number of bats, persons, and date palm sap trees, but had a higher proportion of households in which someone drank sap. Reducing human consumption of sap could reduce virus transmission and risk for emergence of a more highly transmissible NiV strain.