Multifunctional Thrombin-Activatable Polymer Capsules for Specific Targeting to Activated Platelets
Multifunctional Thrombin-Activatable Polymer Capsules for Specific Targeting to Activated Platelets
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DOI：
10.1002/adma.201502243
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发表时间：
2015-09-16
影响因子：
29.4
通讯作者：
Caruso, Frank
中科院分区：
文献类型：
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作者：
Gunawan, Sylvia T.;Kempe, Kristian;Caruso, Frank
Smart poly (2-oxazoline)(POx)-based multifunctional polymer capsules that specifically target glycoprotein (GP) IIb/IIIa on the surface of activated platelets are degraded by the serine protease thrombin and release the urokinase plasminogen activator loaded into the polymer capsules, only in the area of acute thrombosis.
