Assessment of right ventricular remodeling in chronic thromboembolic pulmonary hypertension by 2D-speckle tracking echocardiography: A comparison with cardiac magnetic resonance.
Assessment of right ventricular remodeling in chronic thromboembolic pulmonary hypertension by 2D-speckle tracking echocardiography: A comparison with cardiac magnetic resonance.
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二维斑点追踪超声心动图评估慢性血栓栓塞性肺动脉高压的右心室重构：与心脏磁共振的比较
DOI：
10.3389/fcvm.2022.999389
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发表时间：
2022
影响因子：
3.6
通讯作者：
Guo, Xiaojuan
中科院分区：
文献类型：
--
作者：
Wang, Yeqing;Guo, Dichen;Liu, Mingxi;Zhang, Xinyuan;Hu, Huimin;Yang, Hao;Yang, Yuanhua;Lv, Xiuzhang;Li, Yidan;Guo, Xiaojuan
关键词：
在慢性血栓栓塞性肺动脉高压(CTEPH)患者中，有相当一部分患者会发生右心重构，并显著影响其预后。二维斑点跟踪超声心动图(2D-STE)可用于评价生理和病理条件下的心肌变形。本研究旨在探讨2D-STE评价CTEPH患者右室重构的可行性。本研究对21例CTEPH患者进行了经胸超声心动图(TTE)和心脏磁共振(CMR)检查。收集反映右室功能的参数：三尖瓣环平面收缩期离散度(TAPSE)、面积变化分数(FAC)、右室心肌功能指数(RIMP)、三尖瓣环收缩峰值速度(S‘)和右室射血分数(CMR-RVEF)。使用后处理软件计算了以下应变参数：STE-RV整体纵向应变(STE-RVGLS)、STE-RV自由壁纵向应变(STE-RVFWLS)和CMR-RVGLS。随着CMR-RVEF的恶化，CTEPH患者的右室重构更加明显，主要表现为右室显著增大，心肌变形减弱，右室收缩能力下降(RV面积，STE-RVFWLS，STE-RVGLS：轻度与重度，p<；0.05；CMR-RVGLS：轻度与重度，p<；0.05；Tapse：中度与重度，p<；0.05)。此外，RVFWLS与CMR-RVEF的Pearson相关系数比CMR-GLS更强(r值：0.70比0.68)，2D-STE测量的应变值与右心导管术数据的相关性较弱。BLAND-ALTMAN分析显示，2D-STE和CMR-Feature Tracing(FT)对RVGLS的诊断具有良好的一致性(BISA值=−0.96；95%的符合度在−8.42~6.49之间)。对于RVGLS的测量，2D-STE与CMR-FT同样可行，并能敏感地识别右心重构。
Right heart remodeling occurs in a substantial proportion of patients with chronic thromboembolic pulmonary hypertension (CTEPH) and significantly affects their prognosis. Two-dimensional speckle-tracking echocardiography (2D-STE) can be used to evaluate myocardial deformation under physiological and pathological conditions. This study aimed to assess the feasibility of 2D-STE for evaluating right ventricular (RV) remodeling in CTEPH patients. This retrospective study included 21 CTEPH patients who underwent transthoracic echocardiography (TTE) and cardiac magnetic resonance (CMR). Data for the following parameters that can reflect RV function were collected: tricuspid annular plane systolic excursion (TAPSE), fractional area change (FAC), right ventricular index of myocardial performance (RIMP), peak systolic velocity of the tricuspid annulus (S'), and CMR-right ventricular ejection fraction (CMR-RVEF). The following strain parameters were calculated using post-processing software: STE-RV global longitudinal strain (STE-RVGLS), STE-RV free wall longitudinal strain (STE-RVFWLS), and CMR-RVGLS. As CMR-RVEF deteriorated, RV remodeling in CTEPH patients became more apparent and was mainly characterized by significant enlargement of the RV, weakening of myocardial deformation, and a decrease in RV contractility (RV area, STE-RVFWLS, STE-RVGLS: mild vs. severe and moderate vs. severe, p < 0.05; CMR-RVGLS: mild vs. severe, p < 0.05; TAPSE: moderate vs. severe, p < 0.05). Moreover, the Pearson correlation coefficient for correlation with CMR-derived RVEF was stronger for RVFWLS than for CMR-GLS (r-value: 0.70 vs. 0.68), and the strain values measured by 2D-STE showed a weak correlation with right heart catheterization data. Bland-Altman analysis showed good agreement between 2D-STE and CMR-feature tracking (FT) for RVGLS (bias = −0.96; 95% limit of agreement from −8.42 to 6.49). For the measurement of RVGLS, 2D-STE is similarly feasible to CMR-FT and could sensitively identify right heart remodeling.
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DOI：
10.1111/echo.12716
发表时间：
2015-05
期刊：
Echocardiography (Mount Kisco, N.Y.)
影响因子：
--
作者：
Sanchez AA;Levy PT;Sekarski TJ;Hamvas A;Holland MR;Singh GK
通讯作者：
Singh GK
DOI：
10.1186/s12968-021-00724-5
发表时间：
2021-04-01
期刊：
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
影响因子：
--
作者：
Leng S;Tan RS;Guo J;Chai P;Zhang G;Teo L;Ruan W;Yeo TJ;Zhao X;Allen JC;Tan JL;Yip JW;Chen Y;Zhong L
通讯作者：
Zhong L
影响因子：
2.6
作者：
Hassoun PM;Nikkho S;Rosenzweig EB;Moreschi G;Lawrence J;Teeter J;Meier C;Ghofrani AH;Minai O;Rinaldi P;Michelakis E;Oudiz RJ
通讯作者：
Oudiz RJ
影响因子：
24.3
作者：
Humbert, Marc;Kovacs, Gabor;Rosenkranz, Stephan
通讯作者：
Rosenkranz, Stephan
影响因子：
9.6
作者：
Sachdev, Arun;Villarraga, Hector R.;Kane, Garvan C.
通讯作者：
Kane, Garvan C.