THE ETIOLOGY OF PSYCHIATRIC-SYMPTOMS IN PATIENTS WITH SYSTEMIC LUPUS-ERYTHEMATOSUS
THE ETIOLOGY OF PSYCHIATRIC-SYMPTOMS IN PATIENTS WITH SYSTEMIC LUPUS-ERYTHEMATOSUS
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DOI：
10.3109/03009749409103729
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发表时间：
1994-01-01
影响因子：
2.1
通讯作者：
ANDERSON, KW
中科院分区：
文献类型：
--
作者：
IVERSON, GL;ANDERSON, KW
本综述的目的是探讨SLE患者精神问题的可能病因。虽然精神病的实例通常归因于疾病病理生理学，但这个问题的确切机制仍然是推测性的。非精神病性精神疾患的病因甚至更不清楚。总的来说，SLE患者的精神疾患可能是由许多因素引起的，包括后天性脑功能障碍、器官系统功能障碍、皮质类固醇治疗的医源性影响、学习史、社会心理压力源和当前的应对策略。需要进一步的研究来探索影响个体精神状态的各种生理和心理变量之间的双向、协同和动态相互作用。
The purpose of this review was to explore the probable etiologies of psychiatric problems in patients with SLE. Although instances of psychosis generally are attributed to disease pathophysiology, the precise mechanism for this problem remains speculative. The etiology of non-psychotic psychiatric complaints is even less clear. Overall, it is likely that psychiatric complaints in patients with SLE are attributable to numerous factors including acquired brain dysfunction, organ system dysfunction, iatrogenic effects of corticosteroid treatment, learning history, psychosocial stressors, and current coping strategies. Additional research is needed to explore the bi-directional, synergistic, and dynamic interactions among diverse physiological and psychological variables as they impact an individual's psychiatric status.