Hepatitis B vs. hepatitis C infection on viral hepatitis-associated hepatocellular carcinoma.
Hepatitis B vs. hepatitis C infection on viral hepatitis-associated hepatocellular carcinoma.
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DOI:
10.1186/1471-230x-12-64
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发表时间:
2012-06-08
影响因子:
2.4
通讯作者:
Yee, Herman T
中科院分区:
文献类型:
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作者:
Hiotis, Spiros P;Rahbari, Nuh N;Yee, Herman T
BACKGROUND: To determine clinical-pathologic variables in patients with a new diagnosis of hepatocellular carcinoma (HCC) and underlying hepatitis B vs. C infection.METHODS: Patients presenting to a single urban hospital with a new diagnosis of HCC were entered into a clinical database. Variables including number and size of tumors, presence of metastases, serum alpha-Fetoprotein, hepatitis serologies, severity of hepatic dysfunction, and presence of cirrhosis were evaluated in 127 patients.RESULTS: Patients with hepatitis B (HBV) were more likely to develop HCC at a younger age than patients with hepatitis C (HCV) (HBV-26% under age 40, HCV-0% under age 40; p5cm, HCV-28% >5cm; p