THE EPIDEMIOLOGY AND PREVALENCE OF DIABETIC-RETINOPATHY IN THE VENETO REGION OF NORTH-EAST ITALY
THE EPIDEMIOLOGY AND PREVALENCE OF DIABETIC-RETINOPATHY IN THE VENETO REGION OF NORTH-EAST ITALY
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DOI：
10.1111/j.1464-5491.1991.tb02149.x
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发表时间：
1991-01-01
影响因子：
3.5
通讯作者：
CREPALDI, G
中科院分区：
文献类型：
--
作者：
SEGATO, T;MIDENA, E;CREPALDI, G
在意大利东北部威尼托地区的一项以人群为基础的研究中，研究了糖尿病视网膜病变的患病率及其与一些危险因素的关系。在选择的1321名糖尿病患者中，98%的人参加了检查。糖尿病视网膜病变的患病率为26.2%(背景24.4%，增殖期1.8%)。视网膜病变的患病率与糖尿病病程显著相关(P<；0.01)(5年为17.3%；20年为60.8%)。糖尿病20年后，增殖性视网膜病变更为普遍。10年后，在1型糖尿病患者中发现最多的增殖，但在确诊10年前，它在2型糖尿病中最常见。视网膜病变的患病率与糖尿病的类型显著相关(p<；0.001)，主要见于1型(46.2%)和2型(45.9%)患者，在非胰岛素治疗的患者(24.6%)中程度较小。视网膜病变的患病率与空腹餐后血糖水平(p<；0.001)、血尿素氮水平(p<；0.05)以及收缩压(p<；0.001)和舒张压(p<；0.01)显著相关。在男性和女性之间，完全性视网膜病变或增殖性视网膜病变的患病率没有显著差异。未发现糖尿病家族史、饮酒、吸烟习惯、胆固醇、甘油三酯和血清尿酸与糖尿病家族史有显著关系。
The prevalence of diabetic retinopathy and its relationship to a number of risk factors were examined in a population-based study in the Veneto region of North East Italy. Of 1321 diabetic patients selected, 98 % attended for examination. Prevalence of diabetic retinopathy was 26.2 % (24.4 % background and 1.8 % proliferative). The prevalence of retinopathy was significantly related (p < 0.01) to the duration of diabetes (17.3 % for < 5 years; 60.8 % for > 20 years). Proliferative retinopathy was much more prevalent after 20 years of diabetes. After 10 years most proliferative was found in Type 1 diabetic patients, but before 10 years from diagnosis it was most prevalent in Type 2 diabetes. The prevalence of retinopathy was significantly related (p < 0.001) to the type of diabetes and was found predominantly in Type 1 (46.2 %) and insulin-treated Type 2 (45.9 %) subjects and to a lesser degree in non-insulin-treated patients (24.6 %). The prevalence of retinopathy was significantly related to both fasting post-prandial blood glucose levels (p < 0.001), blood urea nitrogen (p < 0.05), and systolic (p < 0.001) and diastolic (p < 0.01) blood pressure. No significant differences were found in the prevalence of total or proliferative retinopathy between males and females. No significant relationships were found with family history of diabetes, alcohol intake, smoking habits, cholesterol, triglycerides, and serum uric acid.