DESIGN OF THE MAMMALIAN RESPIRATORY SYSTEM .8. CAPILLARIES IN SKELETAL-MUSCLES
DESIGN OF THE MAMMALIAN RESPIRATORY SYSTEM .8. CAPILLARIES IN SKELETAL-MUSCLES
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DOI：
10.1016/0034-5687(81)90080-3
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发表时间：
1981-01-01
期刊：
影响因子：
--
通讯作者：
TAYLOR, CR
中科院分区：
文献类型：
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作者：
HOPPELER, H;MATHIEU, O;TAYLOR, CR
为了确定肌细胞的毛细血管供应如何与其O2需求相匹配，研究了骨骼肌组织中毛细血管密度和线粒体体积密度之间的关系。25种非洲哺乳动物，体重在0.4-251公斤之间。作为一般趋势，较高的毛细血管密度NA（c.f.），在具有较高体积密度的线粒体VV（mt.f）的肌肉中发现。个别数据显示出相当大的分散性。这种分散的一部分可以解释为NA（c.f.）单独不是说明血管供应的功能特性的足够参数。从动脉到静脉端的毛细血管网络的区域变化也有助于数据传播。血管区室的许多生理变量也可能影响毛细血管计数与肌纤维线粒体密度的关系。不能指望这种关系是简单的。
To determine how the capillary supply of muscle cells is matched to their O2 needs, the relationship between capillary density and mitochondrial volume density in skeletal muscle tissue is investigated. 25 African mammals ranging 0.4-251 kg in body mass. As a general trend, higher capillary densities, NA(c.f.), are found in muscles with higher volume densities of mitochondria, VV(mt.f). The individual data show considerable scatter. Part of this scatter can be explained by the fact that NA(c.f.) alone is not a sufficient parameter to account for functional properties of the vascular supply. The regional variability of the capillary network from arterial to venous end also contributes to the data spread. A number of physiological variables of the vascular compartment may also influence the relationship of capillary counts to the mitochondrial densities of muscle fibers. This relationship cannot be expected to be a simple one.