Comparison of inflation of third dose diphtheria tetanus pertussis (DTP3) administrative coverage to other vaccine antigens

Comparison of inflation of third dose diphtheria tetanus pertussis (DTP3) administrative coverage to other vaccine antigens
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DOI:
10.1016/j.vaccine.2017.05.026
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发表时间:
2017-06-14
期刊:
影响因子:
5.5
通讯作者:
MacNeil, Adam
MacNeil, Adam
中科院分区:
医学3区
文献类型:
--
作者:
Dolan, Samantha B.;MacNeil, Adam

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第三剂白喉破伤风百日咳(DTP3)行政覆盖率是免疫规划绩效的常用指标,尽管研究表明DTP3行政覆盖率存在数据质量问题。DTP3的行政覆盖范围可能比其他抗原更大。为了检验这一理论,我们从最近的国家调查(n = 71)中汇编了免疫覆盖率估计值,并将这些估计值与相应的行政覆盖率估计值配对,按国家和队列年,针对DTP3和其他4种抗原。中位行政覆盖率高于所有抗原覆盖率的调查估计值(中位差异为26%至30%),但DTP3的差异与所有其他抗原相似。当各国按收入水平和Gavi供资资格进行分层时,这些结果是一致的。我们的研究结果表明,虽然国家行政覆盖率估计往往高于调查估计,但DTP3行政覆盖率并不比其他抗原更高。爱思唯尔有限公司出版
Third dose diphtheria tetanus pertussis (DTP3) administrative coverage is a commonly used indicator for immunization program performance, although studies have demonstrated data quality issues with administrative DTP3 coverage. It is possible that administrative coverage for DTP3 may be inflated more than for other antigens. To examine this, theory, we compiled immunization coverage estimates from recent country surveys (n = 71) and paired these with corresponding administrative coverage estimates, by country and cohort year, for DTP3 and 4 other antigens. Median administrative coverage was higher than survey estimates of coverage for all antigens (median differences from 26 to 30%), however this difference was similar for DTP3 as for all other antigens. These findings were consistent when countries were stratified by income level and eligibility for Gavi funding. Our findings demonstrate that while country administrative coverage estimates tend to be higher than survey estimates, DTP3 administrative coverage is not inflated more than other antigens. Published by Elsevier Ltd.