Subergane‐Type Sesquiterpenes from Gorgonian Coral Subergorgia suberosa with Antibacterial Activities
Subergane‐Type Sesquiterpenes from Gorgonian Coral Subergorgia suberosa with Antibacterial Activities
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DOI：
10.1002/hlca.201500086
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发表时间：
2015-09
影响因子：
1.8
通讯作者：
Qixi Huang;Wei Cheng;Hailin Long;Huagang Liu;L. Ofwegen;Wenhan Lin
中科院分区：
文献类型：
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作者：
Qixi Huang;Wei Cheng;Hailin Long;Huagang Liu;L. Ofwegen;Wenhan Lin
从柳珊瑚Subergorgia suberosa中分离到一种新的次半萜，命名为环氧次麦草酸(1)，以及7种已知的倍半萜。新化合物的结构是通过广泛的光谱分析确定的。先前不确定的已知类似物2-6的绝对构型是根据CD、Mosher的方法和化学转化确定的。对所有化合物进行抗菌活性评价。
A new subergane-type sesquiterpene, named epoxysubergorgic acid (1), along with seven known sesquiterpenes, were isolated from the gorgonian coral Subergorgia suberosa. The structure of the new compound was determined by extensive spectroscopic analyses. The previously uncertain absolute configuration of the known analogues 2–6 was determined on the basis of CD, Mosher's method, and through chemical conversions. All compounds were evaluated for antibacterial activities.