Cancer increases risk of in-hospital death from COVID-19 in persons
Cancer increases risk of in-hospital death from COVID-19 in persons
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DOI：
10.1038/s41375-020-0986-7
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发表时间：
2020-07-20
期刊：
影响因子：
11.4
通讯作者：
Hu, Yu
中科院分区：
文献类型：
--
作者：
Li, Qiubai;Chen, Lei;Hu, Yu
癌症对2019年冠状病毒病（COVID-19）患者感染急性呼吸道综合征冠状病毒-2（SARS-CoV-2）后预后的影响存在争议。我们研究了来自中国武汉七个中心的1859名COVID-19受试者，其中65人患有癌症。我们发现，在年龄≥ 65岁的人群中，癌症是COVID-19住院死亡的独立风险因素（HR = 1.12 [0.56，2.24];P = 0.740）。它在那些没有完全缓解的人中也更常见。实体癌和血液癌受试者的院内死亡风险相似。这些数据可能有助于预测癌症和COVID-19患者的结果。
The impact of cancer on outcome of persons with coronavirus disease 2019 (COVID-19) after infection with acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is controversial. We studied 1859 subjects with COVID-19 from seven centers in Wuhan, China, 65 of whom had cancer. We found having cancer was an independent risk factor for in-hospital death from COVID-19 in persons = 65 years (HR = 1.12 [0.56, 2.24];P = 0.740). It was also more common in those not in complete remission. Risks of in-hospital death were similar in subjects with solid cancers and those with hematological cancers. These data may help predict outcomes of persons with cancer and COVID-19.