Young women engaged in sex work in Phnom Penh, Cambodia, have high incidence of HIV and sexually transmitted infections, and amphetamine-type stimulant use: new challenges to HIV prevention and risk.
Young women engaged in sex work in Phnom Penh, Cambodia, have high incidence of HIV and sexually transmitted infections, and amphetamine-type stimulant use: new challenges to HIV prevention and risk.
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DOI：
10.1097/olq.0b013e3182000e47
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发表时间：
2011-01
影响因子：
3.1
通讯作者：
Page K
中科院分区：
文献类型：
--
作者：
Couture MC;Sansothy N;Sapphon V;Phal S;Sichan K;Stein E;Evans J;Maher L;Kaldor J;Vun MC;Page K
评估柬埔寨金边从事性工作者(SWS)的年轻女性中艾滋病毒和性传播感染(STI)及其相关危险因素的流行和发病率。一项针对年轻女性(29岁)在妓院、娱乐场所和自由职业者担任性工作者的前瞻性研究。社会人口学、性风险和苯丙胺类兴奋剂(安非他明类兴奋剂)的使用(“雅玛”和“水晶”)通过自我报告进行评估。分别对血液和尿液标本进行HIV和STI(沙眼衣原体和淋球菌)检测。HIV、沙眼衣原体和淋球菌的基线流行率分别为23%、11.5%和7.8%。HIV发病率为3.6/100人年(95%可信区间，1.2%-11.1%)；性传播感染发病率为21.2/100人年(95%CI，12.6%-35.8%)。在基线水平，26.5%的人报告最近使用了ATS。HIV感染与自由职业女性(调整后优势比，5.85；95%CI，1.5 9~2 1.5 8)和初性者年龄较小(≤15岁；调整优势比，3.0 6；95%CI，1.0 1~8.46)有关。事件性传播感染与持续时间(每年)(调整后的风险比，1.1；95%可信区间，1.1-1.2)和最近使用YAMA(调整后的风险比，3.9；95%可信区间，1.5-10.3)有关。在不同环境中工作的性服务人员中，艾滋病毒和性传播感染的比率很高；自由职业者的风险最高。安非他明类药物的使用与事件性传播感染有关。在预防计划中应考虑性工作和毒品预防的地点。
To estimate prevalence and incidence of HIV and sexually transmitted infections (STI) and associated risk factors among young women working as sex workers (SWs) in Phnom Penh, Cambodia. A prospective study of young (<29 years) women working as SWs in brothels, entertainment establishments, and freelance. Sociodemographics, sexual risk, and use of amphetamine-type stimulants (ATS) (“yama” and “crystal”) were assessed by self-report. HIV and STI (Chlamydia trachomatis and Neisseria gonorrhoeae) testing were conducted on blood and urine specimens, respectively. Baseline prevalences of HIV, C. trachomatis, and N. gonorrhoeae were 23%, 11.5%, and 7.8%, respectively. HIV incidence was 3.6 per 100 person-years (95% confidence interval [CI], 1.2%– 11.1%); STI incidence was 21.2 per 100 person-years (95% CI, 12.6%– 35.8%). At baseline, 26.5% reported recent ATS use. HIV infection was associated with freelance SW (adjusted odds ratio, 5.85; 95% CI, 1.59–21.58) and younger age of first sex (≤15 years; adjusted odds ratio, 3.06; 95% CI, 1.01–8.46). Incident STI was associated with duration (per year) of SW (adjusted hazard ratio, 1.1; 95% CI, 1.1–1.2) and recent yama use (adjusted hazard ratio, 3.9; 95% CI, 1.5–10.3). HIV and STI infection rates were high among SWs working in various settings; freelancers had highest risk. ATS use was associated with incident STI. Venue of sex work and drug prevention should be considered in prevention programs.