Drug provocation testing in the diagnosis of drug hypersensitivity reactions: general considerations
Drug provocation testing in the diagnosis of drug hypersensitivity reactions: general considerations
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DOI：
10.1034/j.1398-9995.2003.00279.x
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发表时间：
2003-09-01
期刊：
影响因子：
12.4
通讯作者：
Demoly, P
中科院分区：
文献类型：
--
作者：
Aberer, W;Bircher, A;Demoly, P
药物激发试验(DPT)是为了诊断药物过敏反应而进行的受控给药。DPTS是在医学监督下进行的，无论该药物是替代化合物，或结构/药理相关，或可疑药物本身。DPT有时被称为受控挑战或再暴露(1)、药物挑战(2)、分级(2)或递增挑战(3)、试验剂量(2)、
A drug provocation test (DPT) is the controlled administration of a drug in order to diagnose drug hypersensitivity reactions. DPTs are performed under medical surveillance, whether this drug is an alternative compound, or structurally/pharmacologically related, or the suspected drug itself. DPT is sometimes termed controlled challenge or reexposure (1), drug challenge (2), graded (2) or incremental challenge (3), test dosing (2),