Prevalence of malaria parasites in adults and its determinants in malaria endemic area of Kisumu County, Kenya
Prevalence of malaria parasites in adults and its determinants in malaria endemic area of Kisumu County, Kenya
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DOI：
10.1186/s12936-015-0781-5
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发表时间：
2015-07-08
期刊：
影响因子：
3
通讯作者：
Ogutu, Bernhards
中科院分区：
文献类型：
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作者：
Jenkins, Rachel;Omollo, Raymond;Ogutu, Bernhards
背景：疟疾寄生虫在非洲成人中的流行情况没有在儿童中得到很好的研究。为此，利用人口监测点对维多利亚湖附近的基苏木县马塞诺分区疟疾流行区成年人进行了入户调查。方法：随机调查70805人口疟疾流行区人口健康监测点的1190名成年人，用玻片显微镜测量疟疾寄生虫的存在。结果：马塞诺市成人疟疾寄生虫感染率为28%(95%可信区间：25.4~31.0%)。在单变量(OR1.5，p=0.005)和多变量(OR1.4，p=0.019)分析中，性别都是显著的社会人口学危险因素。女性疟疾患病率比男性高50%。结论：疟疾流行地区成年人群中疟疾寄生虫普遍存在，且女性疟疾感染率明显升高。这种成人库疟疾寄生虫的存在是将寄生虫传播给儿童的关键储存因素，并与根除疟疾的计划有关。
Background: The prevalence of malaria parasites in adults in Africa is less well researched than in children. Therefore, a demographic surveillance site was used to conduct a household survey of adults in the malaria endemic area of Maseno division in Kisumu County near Lake Victoria.Methods: A random survey of 1,190 adults living in a demographic health surveillance site in a malaria endemic area of 70,805 population size was conducted, measuring presence of malaria parasites by slide microscopy. Data were analysed using STATA to calculate the prevalence of malaria and associated risk factors.Results: The adult prevalence of presence of malaria parasites in Maseno was 28% (95% CI: 25.4-31.0%). Gender was a significant sociodemographic risk factor in both univariate (OR 1.5, p = 0.005) and multivariate (OR 1.4, p = 0.019) analyses. Females were 50% more likely to have malaria than men.Conclusions: Presence of malaria parasites is common in the adult population of this endemic area, and the rate is greatly increased in women. The presence of such an adult pool of malaria parasites represents a key reservoir factor in transmission of parasites to children, and is relevant for plans to eradicate malaria.