FLOW OF EXCITATION WITHIN RAT BARREL CORTEX ON STRIKING A SINGLE VIBRISSA
FLOW OF EXCITATION WITHIN RAT BARREL CORTEX ON STRIKING A SINGLE VIBRISSA
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DOI：
10.1152/jn.1992.68.4.1345
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发表时间：
1992-10-01
影响因子：
2.5
通讯作者：
DASGUPTA, A
中科院分区：
文献类型：
--
作者：
ARMSTRONGJAMES, M;FOX, K;DASGUPTA, A
1.用乌拉坦麻醉的成年大鼠，在皮层不同层的单个细胞中进行细胞外锋电位记录。对简报1的反应幅度和潜伏期差异。14-测量中心（主）和周围感受野触须的肌触须偏转度。还收集了相同穿透中的成对细胞对刺激主触须的潜伏期差异。在单独的实验中，IV层细胞的域被映射为它们受单个触须的影响，并且记录它们对该触须的依赖。在所有的实验中，每一次穿透中IV层细胞的精确位置都是通过切向切片的染料损伤和细胞色素氧化酶染色来确定的.结果表明，主要触须数据中继径向在一列的神经元平行中继到相邻的列之前。对于主触须，IV层和Vb层神经元放电最早，II层和III层平均分别为2和3 ms。从第四层到第三层到第二层的串行继电器被认为是最常见的事件。虽然第Va层细胞发射下，单列组织不建议他们，因为他们的主要和直接周围触须的延迟或响应幅度的差异并不显着。第二、三、四层细胞对周围触须的潜伏期无统计学差异，但放电时间明显晚于对主要输入的放电时间.因为，从我们以前的研究，在大鼠S1皮层的桶形细胞周围的感受野似乎是在皮层内构建的，这些数据表明，它们的建设平行柱-柱继电器。筒间水平接力首先发生在筒间隔膜内。平均皮质内传输速度计算约为0.05米/秒的柱柱信息传输。
1. Extracellular spike recordings were made from single cells in various layers of barrel cortex in adult rats anesthetized with urethan. Response magnitude and latency differences to brief 1. 14-degrees deflections of mystacial vibrissae of center (principal) and surround receptive-field vibrissae were measured. Latency differences for pairs of cells in the same penetration to stimulation of the principal vibrissa were also collected. In separate experiments the domains of layer IV cells were mapped for their influence by a single vibrissa and their latencies to this vibrissa were recorded. In all experiments precise locations of layer IV cells in each penetration were identified using dye-lesioning and cytochrome oxidase staining of tangential sections.2. The results suggest that principal vibrissa data are relayed radially in a column of neurons before parallel relay to adjacent columns. To the principal vibrissa, layers IV and Vb neurons discharged earliest, with layers II and III on average 2 and 3 ms later, respectively. Serial relay from layers IV to III to II was suggested to be the most common event. Although layer Va cells fired next, a single-column organization is not suggested for them because differences in latency or response magnitude to their principal and immediate surround vibrissae were not significant. Layer II, III, and IV cells showed no statistical difference in latency to the nearest surround vibrissa but fired significantly later than to their principal input.3. Because, from our previous studies, surround receptive fields of barrel cells in rat S1 cortex appear to be constructed intracortically, these data suggest a parallel column-column relay for their construction. Horizontal relay between barrels occurred first within the septae between barrels. Mean intracortical transmission velocities were calculated at approximately 0.05 m/s for column-column information transfer.